Diagnostic Tests Flashcards
Testing for autoimmune condition (4)
Increased
Erythrocyte sedimentation rate (ESR) - sign of inflammation
C-Reactive Protein (CRP) - sign of inflammation
Positive rheumatoid factor (RF) antibodies - sign of autoimmune
Positive anti-nuclear antibody (ANA) - sign of autoimmune
Rheumatoid arthritis
all 4 standard autoimmune tests + positive anti-citrullinated peptide antibody (ACPA)
Systemic Lupus Erythematosus (SLE)
all 4 standard autoimmune tests + positive anti-dsDNA antibodies
Multiple Sclerosis
MRI
anemia
Low Hgb, RBC, Hct
If microlytic (iron deficiency related), decreased MCV < 80 because RBCs are smaller
if macrolytic (B12 or folate deficiency) increased MCV >100 because RBCs are bigger via schilling test
Venous Thromboembolism (VTE)
D-dimer test (marker of fibrinolysis) , positive is sign of blood clot
DVT: ultrasound (US) , venography, or MRI
PE: pulmonary computed tomographic anigiography (CTA)
Stroke prevention
CHA2DS2-VASc
CHF
HTN
Age > 65 =1 pt, >75 = 2 pt
DM
Stroke/Transischemic Attack = 2 pt
VA = vascular disease or previous MI
Sc = sex category
Patients with 2 or more points are to be treated with full anticoagulation and anyone with 1 can be on ASA
Heparin induced thrombocytopenia
Unexplained drop in platelets >50% from baseline 5-14 days after starting heparin
positive antibodies revealed on a heparin platelet factor 4 (PF4) ELISA and/or serotonin release assay
ACS
ECG or EKG (electrocardiogram) (to understand the rhythm and function of the heart)
Cardiac enzymes like creatine kinase muscle/brain (CK-MB), troponin I, T
ECG /EKG vs Echo
ECG/EKG are both aka electrocardiograms where a provider will be able to hear the hearts rhythm and function “hear the heart”. Echocardiogram aka Echo is just a heart ultrasound to be able to see the heart.
Arrythmias
ECG/EKG, Holter monitor (portable device), HR
Cerebrovascular accident (CVA or stroke)
Computed tomography (CT), MRI
Chronic Heart Failure
ECHO, increased B type Natriuretic peptide (BNP), increased N-terminal pro BNP (NT-proBNP)
Stable Ischemic Heart Disease (SIHD)/Chronic Stable Angina)
Cardiac stress test, angiography
Dyslipidemia
Increased TC, non-HDL, TGs, coronary artery calcium (CAC- non invasive scan of heart measuring calcium containing plaque)
HTN
increased systolic and diastolic BP
Hypertensive emergency
> /= 180/120mmHg with sign of acute target organ damage
(chest discomfort (myocardial ischemia or MI), back pain (aortic dissection), altered level of consciousness, headache, visual disturbances (hypertensive encephalopathy), or shortness of breath)
Hypertensive urgency
> /=180/120 WITHOUT sign of acute target organ damage
(chest discomfort (myocardial ischemia or MI), back pain (aortic dissection), altered level of consciousness, headache, visual disturbances (hypertensive encephalopathy), or shortness of breath)
10 year risk for atherosclerotic CVD
Use the calculator if they haven’t had any ASCVD history in the past. ACS/IHD, stroke, PAD.
Diabetes/prediabetes
FBG, OGTT, A1c
Hyperthyroidism
decreased TSH, increased free T4 (FT4)
Hypothyroidism
increased TSH, decreased free T4 (FT4)
Ovulation
LH - when it’s at its peak. This is the optimal time for intercourse to become pregnant
Pregnancy
Positive human chorionic gonadotropin (hCG) in urine (at home test) or blood
Bacterial vaginitis
Clear white or gray vaginal discharge with a fishy odor and pH > 4.5 little or no pain.
Candida vaginitis
White, thicker vaginal discharge, pruritis (itchy itchy)
Trichomoniasis
Yellow, green, frothy, foul smelling vaginal discharge =, pH > 4.5, soreness and pain with sex
Peptic Ulcer Disease
Upper gastrointestinal endoscopy (mouth to small intestine
Duodenal ulcer - pain whenever food is not in stomach and 2-3 hrs after eating. pain relief with food and antacids
Gastric ulcer - pain whenever food is in the stomach, little to no pain relief with food and antacids
GERD
Esophogeal pH monitoring , endoscopy
H. Pylori
Urea breath test (UBT), fecal antigen test
Inflammatory bowel disease (Ulcerative colitis, crohn’s disease)
Endoscopy (for crohn’s disease, which affects any part of the GI tract)
Sigmoidoscopy (for ulcerative colitis, which affects the colon (large intestine) and rectum)