Diagnosis of B12/Folate deficiency Flashcards
1
Q
Serum B12 immunoassay level for diagnosis of B12/folate deficiency
A
Over 220 pm/L is normal, less than 150 is low
2
Q
Why is serum a poor measure of diagnosing folate deficiency?
A
Poor measure because it is modified easily with a large meal
3
Q
Why is RBC the best measure for diagnosing folate deficiency?
A
Normal red cell level is 320-1370 (large range)
4
Q
Homocysteine levels are _______ in both B12 and folate deficiency.
A
Increased homocysteine levels
5
Q
Which acid is measured in the serum and urine for B12 deficiency?
A
Methylmalonic acid
6
Q
What causes ‘reduced haptocorrin (TCI) levels’?
A
Pregnancy, neutropenic state/aplastic anaemia
