Diabetics Flashcards
Oral Agents: Class RX Tolbutamide MOA SE Contraindications
Sulfonylurea
Binds to sulfonylurea receptors on Bcells; \A1c1-2%
Hypoglycemia, Weight gain, Nausea, rash, itching
Type 1DM, Bad Liver Kidney and risk of \BS
Gut Hormones:Incretin Hormone namesFunction for CHO Metab.
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GLP-1MOASEContraindications
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Amylin Analog:MOASEContraindications
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DPP-!V i.MOASEContraindications
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Oral Agents: Class RX Tolazamide MOA SE Contraindications
Sulfonylurea
Binds to sulfonylurea receptors on Bcells; \A1c1-2%
Hypoglycemia, Weight gain, Nausea, rash, itching
Type 1DM, Bad Liver Kidney and risk of \BS
Oral Agents: Class RX Chlorpropamide MOA SE Contraindications
Sulfonylurea
Binds to sulfonylurea receptors on Bcells; \A1c1-2%
Hypoglycemia, Weight gain, Nausea, rash, itching
Type 1DM, Bad Liver Kidney and risk of \BS
Oral Agents: Class RX Glyburide MOA SE Contraindications
Sulfonylurea
Binds to sulfonylurea receptors on Bcells; \A1c1-2%
Hypoglycemia, Weight gain, Nausea, rash, itching
Type 1DM, Bad Liver Kidney and risk of \BS
Oral Agents: Class RX Glipizide MOA SE Contraindications
Sulfonylurea
Binds to sulfonylurea receptors on Bcells; \A1c1-2%
Hypoglycemia, Weight gain, Nausea, rash, itching
Type 1DM, Bad Liver Kidney and risk of \BS
Oral Agents: Class RX Glimepiride MOA SE Contraindications
Sulfonylurea
Binds to sulfonylurea receptors on Bcells; \A1c1-2%
Hypoglycemia, Weight gain, Nausea, rash, itching
Type 1DM, Bad Liver Kidney and risk of \BS
Oral Agents: Class RX Replaglinide MOA SE Contraindications
Meglitinide
Faster binding to sulfonylurea receptors on Bcells; \A1c1-2%
Hypoglycemia, Weight gain, Nausea
Type 1DM, Bad Liver Kidney and risk of \BS
Oral Agents: Class RX Nateglinide MOA SE Contraindications
D-phenylalanine Derivative
glucose dependent insulin secretion after meals. Hypoglycemia, Weight gain.
Type 1DM, Bad Liver.
Oral Agents: Class RX Metformin MOA SE Contraindications
Biguanides
Activates AMP protein kinase, \hepatic gluconeogenesis, \intestinal glucose absorption, /insulin sensitivity, \A1c 1%
NVD 20% & Lactic acidosis
Bad Liver & kidney
Oral Agents: Class RX Pioglitazone MOA SE Contraindications
Thiazolidinediones
/sensitivity on PPAR gamma receptors in musclefat&liver, \Hepatic output, \A1c 1%
Weight gain, LE edema, /MI, \BMD, /bladder ca.
Oral Agents: Class RX Rosiglitazone MOA SE Contraindications
Thiazolidinediones
/sensitivity on PPAR gamma receptors in musclefat&liver, \Hepatic output, \A1c 1%
Weight gain, LE edema, /MI, \BMD, /bladder ca.