Diabetics Flashcards

1
Q
Oral Agents: 
Class
RX Tolbutamide
MOA
SE
Contraindications
A

Sulfonylurea
Binds to sulfonylurea receptors on Bcells; \A1c1-2%
Hypoglycemia, Weight gain, Nausea, rash, itching
Type 1DM, Bad Liver Kidney and risk of \BS

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2
Q

Gut Hormones:Incretin Hormone namesFunction for CHO Metab.

A

.

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3
Q

GLP-1MOASEContraindications

A

.

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4
Q

Amylin Analog:MOASEContraindications

A

.

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5
Q

DPP-!V i.MOASEContraindications

A

.

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6
Q
Oral Agents:
Class
RX Tolazamide
MOA
SE
Contraindications
A

Sulfonylurea
Binds to sulfonylurea receptors on Bcells; \A1c1-2%
Hypoglycemia, Weight gain, Nausea, rash, itching
Type 1DM, Bad Liver Kidney and risk of \BS

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7
Q
Oral Agents:
Class
RX Chlorpropamide
MOA
SE
Contraindications
A

Sulfonylurea
Binds to sulfonylurea receptors on Bcells; \A1c1-2%
Hypoglycemia, Weight gain, Nausea, rash, itching
Type 1DM, Bad Liver Kidney and risk of \BS

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8
Q
Oral Agents: 
Class
RX Glyburide
MOA
SE
Contraindications
A

Sulfonylurea
Binds to sulfonylurea receptors on Bcells; \A1c1-2%
Hypoglycemia, Weight gain, Nausea, rash, itching
Type 1DM, Bad Liver Kidney and risk of \BS

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9
Q
Oral Agents:
Class
RX Glipizide
MOA
SE
Contraindications
A

Sulfonylurea
Binds to sulfonylurea receptors on Bcells; \A1c1-2%
Hypoglycemia, Weight gain, Nausea, rash, itching
Type 1DM, Bad Liver Kidney and risk of \BS

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10
Q
Oral Agents:
Class
RX Glimepiride
MOA
SE
Contraindications
A

Sulfonylurea
Binds to sulfonylurea receptors on Bcells; \A1c1-2%
Hypoglycemia, Weight gain, Nausea, rash, itching
Type 1DM, Bad Liver Kidney and risk of \BS

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11
Q
Oral Agents:
Class
RX Replaglinide
MOA
SE
Contraindications
A

Meglitinide
Faster binding to sulfonylurea receptors on Bcells; \A1c1-2%
Hypoglycemia, Weight gain, Nausea
Type 1DM, Bad Liver Kidney and risk of \BS

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12
Q
Oral Agents:
Class
RX Nateglinide
MOA
SE
Contraindications
A

D-phenylalanine Derivative
glucose dependent insulin secretion after meals. Hypoglycemia, Weight gain.
Type 1DM, Bad Liver.

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13
Q
Oral Agents:
Class
RX Metformin
MOA
SE
Contraindications
A

Biguanides
Activates AMP protein kinase, \hepatic gluconeogenesis, \intestinal glucose absorption, /insulin sensitivity, \A1c 1%
NVD 20% & Lactic acidosis
Bad Liver & kidney

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14
Q
Oral Agents:
Class
RX Pioglitazone
MOA
SE
Contraindications
A

Thiazolidinediones
/sensitivity on PPAR gamma receptors in musclefat&liver, \Hepatic output, \A1c 1%
Weight gain, LE edema, /MI, \BMD, /bladder ca.

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15
Q
Oral Agents:
Class
RX Rosiglitazone
MOA
SE
Contraindications
A

Thiazolidinediones
/sensitivity on PPAR gamma receptors in musclefat&liver, \Hepatic output, \A1c 1%
Weight gain, LE edema, /MI, \BMD, /bladder ca.

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16
Q
Oral Agents:
Class
RX Acarbose
MOA
SE
Contraindications
A

Alpha-Glucosidase I.
Delay absorption of starch, \A1c 1%.
Farts from colon.
bad kidneyliverintestine

17
Q
Oral Agents:
Class
RX Miglitol
MOA
SE
Contraindications
A

Alpha-Glucosidase I.
Delay absorption of starch, \A1c 1%.
Farts from colon.
bad kidneyliverintestine