Diabetic Retinopathy Flashcards
What is Diabetic retinopathy?
Retinal vasculopathy due to DM
Which vessels are affected in diabetic retinopathy?
Precapillary aaa, vvv + capillaries
What is the incidence of DR most related to?
Duration of DM
RF DR (8)
Duration DM*** Age Smoking Control DM (poor) HTN Hyperlipidaemia Renal impairment Pregnancy
How long after having DM does NPDR tend to occur?
> 8-10years after
Features NPDR on fundoscopy (7)
Microaneurysms Exudates Retinal haemorrhages CW spots Vascular dilatations Calibre variations Intraretinal microvascular abnormalities (IRMA)
What is a microaneurysm
Focal dilatations of retinal capillaries which leak
What is a haemorrhage
Dot (small)
Blot (large) from vv reintal caps
Flame = nn fibre layer
What is a CW spot
Greyish white, fluffy edged lesions in nn fibre layer (axoplasmic accum)
If NPDR is severe, how long will it be until it becomes PDR?
12 months
What % people with DM have PDR?
5%
Which type of diabetes is more susceptible to PDR?
T1DM
Features early PDR
Neovascularisation
Fragile –> vitreious haemorrhage
What vasculature is affected in PDR?
vv
Late changes PDR (3)
Retinal fibrosis
Traction - retinal detachment
Rubeosis iridis + neovascular glaucoma