Diabetes tests and levels and drugs Flashcards
Give three prediabetes tests
fasting plasma glucose and oral glucose tolerance test and HBA1C
Give the prediabetes values for fasting plasma glucose test
100-125mg/dl
Give normal values for fasting plasma glucose
less than 100mg/dl
predia values for oral glu tol
140-199 mg/dl
norm values for oral glu tol
less than 140mg/dl
predia values for HBA1C
5.7%-6.4%
norm values for HBA1C
5.6%
What is HBA1C?
glycated haemoglobin, formed in a glycation pathway by haemoglobins exposure to plasma glucose, as average plasma glucose increases, HBA1C increases. once glycated, stays so. HPLC and immunoassays used.
how long to fast for fasting plasma glucose?
8hrs
What are the two drugs prescribed?
metformin and rampiril
What is metformin?
suppresses glucose production by the liver, reduces LDL levels triglyceride levels. increases uptake of glucose by skeletal muscle. Only oral drug that doesnt cause weight gain, but can cause lactic acidosis.
what is rampiril?
an ace inhibitor, results in the relaxation of smooth muscle via downregulation of angiotensin and therefore reduces BP.