Diabetes Medications Flashcards

1
Q

How does Metformin work?

A

Lowers basal and postmeal glucose by reducing hepatic glucose production and improving tissue sensitivity to insulin

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2
Q

what type of drug is Metformin?

A

bigunides

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3
Q

How should Metformin be taken?

A

with food

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4
Q

What risk factors are contraindicated for Metformin?

A

lactic acidosis, reduced kidney function, liver impairment, respiratory insufficiency, severe infection, alcohol abuse, CHF

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5
Q

How do Thiazolidiones work?

A

improve insulin sensitivity and reduce liver glucose production

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6
Q

Examples of rapid acting insulin

A

NovoLog
Apidra
Humalog

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7
Q

Examples of short acting insulin

A

Humulin R
Novolin R
ReliOn R

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8
Q

Examples of intermediate acting insulin

A

Humulin N, Humulin 70/30, Humulin 50/50
Novolin N, Novolin 70/30
ReliOn N, ReliOn 70/30

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9
Q

Examples of long acting insulin

A

Lantus

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10
Q

When should regular insulin be injected?

A

20 to 30 min before meal

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11
Q

Can insulin glargine be mixed with other forms of insulin?

A

no

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12
Q

List some complications of using a continuous subcutaneous infusion of insulin (CSII)

A

skin infections, hyperglycemia, more sever ketoacidosis

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13
Q

How long can insulin in use be stored?

A

At room temp for up to 28 days

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14
Q

How should insulin not in use be stored?

A

Refrigerated

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15
Q

List rapid acting insulin

A

lispro (Humalog)
aspart (Novolog)
glulisine (Apidra)

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16
Q

Name short-acting to insulins

A

Humulin R

Novolin R

17
Q

Name intermediate-acting insulins

A

Humulin N

Novolin N

18
Q

Name like long-acting insulins

A

glargine (Lantus)

detemir (Levemir)

19
Q

Rapid acting onset, peak, duration

A

Onset 10-30 min
Peak 30-3 hrs
Duration 3-5 hrs

20
Q

Short acting peak, onset, duration

A

Onset 30 min - 1 hr
Peak 2-5 hrs
Duration 5-8 hrs