Diabetes Medications Flashcards
Gliptin =
DPP4
DPP4 =
gliptin
Sulfonylurea
Gliclazide
Glimepiride
Tolbutamide
GLP1
Exanatide
Thiazalidinidiones
Pioglitazone
SGLT2
Canagliflozin
Weight neutral
DPP4
Weight gain
Sulfonylurea
Thiazalidinidiones
Weight loss
SGLT2
GLP1
Pioglitazone SE (6)
Bladder ca
Osteoporosis
Liver impairment
Weight gain
CI heart failure
Fluid retention
SGLT2 SE (4)
Increased risk of amputation
Fourniere’s gangrene
Urinary and genital infections
Weight loss
GLP1 mimetics SE (2)
Pancreatitis
Weight loss
DPP4 SE (1)
weight neutral
Sulfonylurea SE (6)
Weight gain
Hypoglycaemia
SIADH
Cholestasis
Peripheral neuropathy
Bone marrow suppression
Targets
One oral hypoglycaemic
or just lifestyle
48
If rises to? then add in second agent and target will be?
58 then 53
If any BG of chronic heart failure or established CVD offer?
SGLT2 with metformin
SGLT2 can only be given with which two drugs?
metformin and a sulfonylurea