Auto-antibodies 1 Flashcards
Ank spond
HLA B27
p-ANCA
Churg Strauss (eosinophilic granulomatosis)
Microscopic polyangitis
c-ANCA
Wegener’s/ granulomatosis polyangitis
p-ANCA other associations (4)
UC
PSC
Crohn’s
Anti-GBM
HLA B51
Behcets
Behcets
HLA B51
Dermatomyositis (2)
ANA (80%)
Anti Jo1 Anti Mi 2 (30%)
Drug induced lupus
+ve (2) and -ve
ANA 100% +ve
anti-histone 90%
dsDNA negative
HLA A3
Haemochromatosis
HLA B27 (3)
Ank spond
RA
Acute anterior uveitis
HLA DQ2/DQ8
Coeliac
anti-Jo1 anti-Mi2
Polymyositis/ dermatomyositis
Anti Ro La + ANA (70%) (50% RhF)
Sjogren’s
SLE (3)
ANA
anti-dsDNA
anti-Smith
Systemic sclerosis
Antibodies
Diffuse
Limited
ANA 90%
Diffuse - scl-70 antibodies
Limited - anti-centromere
Scl 70 antibodies
Diffuse systemic sclerosis
Anti-centromere
Limited systemic sclerosis
Anti-histone
Drug induced SLE
Tower of 2
15 months
Tower of 3
18 months
Tower of 6
2 years
Tower of 9
3 years
Line
2
Circle
3
Cross
4
Square and triangle
5
Scribble
18 months
200 words
2.5 years
Short sentences
Identifies colours
Counts to 10
3yo
Asks why, when, how
4yo
Asks what who
3yo
Turns towards sound
3 months
Double syllables
6 months
Mama and dada
9 months
Responds to name
12 months
Combines 2 words in sentences
2yo