Auto-antibodies 1 Flashcards

1
Q

Ank spond

A

HLA B27

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2
Q

p-ANCA

A

Churg Strauss (eosinophilic granulomatosis)
Microscopic polyangitis

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3
Q

c-ANCA

A

Wegener’s/ granulomatosis polyangitis

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4
Q

p-ANCA other associations (4)

A

UC
PSC
Crohn’s
Anti-GBM

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5
Q

HLA B51

A

Behcets

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6
Q

Behcets

A

HLA B51

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7
Q

Dermatomyositis (2)

A

ANA (80%)
Anti Jo1 Anti Mi 2 (30%)

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8
Q

Drug induced lupus
+ve (2) and -ve

A

ANA 100% +ve
anti-histone 90%
dsDNA negative

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9
Q

HLA A3

A

Haemochromatosis

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10
Q

HLA B27 (3)

A

Ank spond
RA
Acute anterior uveitis

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11
Q

HLA DQ2/DQ8

A

Coeliac

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12
Q

anti-Jo1 anti-Mi2

A

Polymyositis/ dermatomyositis

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13
Q

Anti Ro La + ANA (70%) (50% RhF)

A

Sjogren’s

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14
Q

SLE (3)

A

ANA
anti-dsDNA
anti-Smith

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15
Q

Systemic sclerosis
Antibodies
Diffuse
Limited

A

ANA 90%
Diffuse - scl-70 antibodies
Limited - anti-centromere

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16
Q

Scl 70 antibodies

A

Diffuse systemic sclerosis

17
Q

Anti-centromere

A

Limited systemic sclerosis

18
Q

Anti-histone

A

Drug induced SLE

19
Q

Tower of 2

A

15 months

19
Q

Tower of 3

A

18 months

20
Q

Tower of 6

A

2 years

21
Q

Tower of 9

A

3 years

22
Q

Line

A

2

23
Q

Circle

A

3

24
Q

Cross

A

4

25
Q

Square and triangle

A

5

26
Q

Scribble

A

18 months

27
Q

200 words

A

2.5 years

28
Q

Short sentences
Identifies colours
Counts to 10

A

3yo

29
Q

Asks why, when, how

A

4yo

30
Q

Asks what who

A

3yo

31
Q

Turns towards sound

A

3 months

32
Q

Double syllables

A

6 months

33
Q

Mama and dada

A

9 months

34
Q

Responds to name

A

12 months

35
Q

Combines 2 words in sentences

A

2yo