Auto-antibodies 1 Flashcards
1
Q
Ank spond
A
HLA B27
2
Q
p-ANCA
A
Churg Strauss (eosinophilic granulomatosis)
Microscopic polyangitis
3
Q
c-ANCA
A
Wegener’s/ granulomatosis polyangitis
4
Q
p-ANCA other associations (4)
A
UC
PSC
Crohn’s
Anti-GBM
5
Q
HLA B51
A
Behcets
6
Q
Behcets
A
HLA B51
7
Q
Dermatomyositis (2)
A
ANA (80%)
Anti Jo1 Anti Mi 2 (30%)
8
Q
Drug induced lupus
+ve (2) and -ve
A
ANA 100% +ve
anti-histone 90%
dsDNA negative
9
Q
HLA A3
A
Haemochromatosis
10
Q
HLA B27 (3)
A
Ank spond
RA
Acute anterior uveitis
11
Q
HLA DQ2/DQ8
A
Coeliac
12
Q
anti-Jo1 anti-Mi2
A
Polymyositis/ dermatomyositis
13
Q
Anti Ro La + ANA (70%) (50% RhF)
A
Sjogren’s
14
Q
SLE (3)
A
ANA
anti-dsDNA
anti-Smith
15
Q
Systemic sclerosis
Antibodies
Diffuse
Limited
A
ANA 90%
Diffuse - scl-70 antibodies
Limited - anti-centromere