Diabetes insipidus Flashcards

1
Q

causes of diabetes inspidius ?

A

cranial (decreased ADH production)

  • idiopathic
  • head trauma
  • pituitary surgery
  • DIDMOAD
  • craniopharyngioma
  • haemochromatosis

nephrogenic (decreased ADH sensitivity)

  • tubuo-interstitial - obstruction, pyelonephritis, sickle cell
  • drugs e.g. lithium
  • genetic
  • hypercalcaemia, hypokalaemia
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2
Q

treatment for cranial diabetes insipidus ?

A

desmopressin

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3
Q

treatment for nephrogenic diabetes insipidus ?

A

thiazide like diuretics

low salt and protein diet

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4
Q

features of diabetes insipidus ?

A

polyuria
polydipsia
high plasma osmolality and low urine osmolality

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