Diabetes insipidus

Question 1

anti diuretic hormone is produced by the

Answer 1

hypothalamus gland

Question 2

anti diuretic hormone allows for decreased _______ output & increase in __________

Answer 2

• urine output

- water absorption in the kidneys

Question 3

anti diuretic hormone is stored in the

Answer 3

posterior pituitary gland

Question 4

Diabetes is caused by an

Answer 4

deficiency of or decreased response to ADH within the body

Question 5

two kinds of Diabetes insipidus

Answer 5

neurogenic (central)

nephrogenic

Question 6

diabetes insipidus prevents people from

Answer 6

appropriately concentrating urine & reabsorbing water, especially problematic in times of water restriction or unavailability

Question 7

Neurogenic or central (Diabetes insipudus)

Answer 7

occurs when body is unable to or is deficient in the production or release of ADH

Question 8

Nephrogenic Diabetes insipidus

Answer 8

occurs when kidneys do not respond appropriately to the presence of ADH

Question 9

Two forms of Diabetes insipidus are similar in that both result in

Answer 9

exaggerated fluid intake & urine output and are both ADH disorders

Question 10

Differences: Neurogenic (central) DI

Answer 10

• may be due to trauma
• may be temporary (ex head injury or surgery)
• ability to concentrate some urine

Question 11

Differences: Nephorgenic DI

Answer 11

• may be genetic or accquired etiology

- effects are permanent and may include hypokalemia or hypercalcemia

Question 12

Cheif mnfts of diabetes insipidus

Answer 12

• excessive thirst

- large urine output

Question 13

potential complications of diabetes insipidus

Answer 13

• electrolyte imbalances
• dehydration
• these comlications may cause muscle weakness, hypotension, hypternatremia, tachycardia

Question 14

diagnosing DI

Answer 14

• thorough 24 hr documentation of urine output recorded
• doctors must disqualify kidney disease & glucose as potential causes of excessive urine output
• ADH levels along with plasma & urine osmolartiy will be tested before & after fluid deprivation
• pharmacological tests may b administered via introdoucing ADH, nephrogenic Di wil not respond to theses drugs as ADH receptors are what is damaged
• if neurogeinc MRI of pituitary hypothalamic region

Question 15

Treatment for neurogenic

Answer 15

• manage disorder by drinking water when thirsty and may receive pharmacological ADH supplements in order to recftify deficeney
• respond to thiazide diuretics (aids body in sodium & water reabsorption in kidneys)

Question 16

Treatment for nephrogenic

Answer 16

-respond to thiazide diuretics (aids body in sodium & water reabsorption in kidneys)