Diabetes Insipidus Flashcards
diabetes insipidus
abnormal quantity/response to ADH
causes
cranial:
trauma
infection
inflammation
nephrogenic:
lithium
electrolyte imbalance
CKD
signs
large volumes of urine
low osmolality
excessive thirst
nocturia
investigations
water deprivation test/desmopressin
management
cranial:
desmopressin
nephrology:
thiazide diuretic
what are the causes for a quantity and response issue
quantity - cranial
response - nephrogenic
what will be the results of the investigations
high plasma osmolality
low urine osmolality
what are the results from a water deprivation test
cranial - low after fluid deprivation, high after ADH
nephrogenic - low after fluid deprivation and after ADH
primary polydyspesia - high after fluid deprivation and after ADH