Diabetes Insipidus Flashcards

1
Q

diabetes insipidus

A

abnormal quantity/response to ADH

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2
Q

causes

A

cranial:
trauma
infection
inflammation

nephrogenic:
lithium
electrolyte imbalance
CKD

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3
Q

signs

A

large volumes of urine
low osmolality
excessive thirst
nocturia

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4
Q

investigations

A

water deprivation test/desmopressin

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5
Q

management

A

cranial:
desmopressin

nephrology:
thiazide diuretic

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6
Q

what are the causes for a quantity and response issue

A

quantity - cranial

response - nephrogenic

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7
Q

what will be the results of the investigations

A

high plasma osmolality

low urine osmolality

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8
Q

what are the results from a water deprivation test

A

cranial - low after fluid deprivation, high after ADH
nephrogenic - low after fluid deprivation and after ADH
primary polydyspesia - high after fluid deprivation and after ADH

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