Acromegaly Flashcards

1
Q

acromegaly

A

excess GH secretion causing excess IGF-1

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2
Q

causes

A

pituitary adenoma

ectopic GHRH tumours (small percent)

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3
Q

signs

A
large feet, hands, mouth, nose
sweating
headaches
day time sleepiness
coarsening features
pituitary adenoma features
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4
Q

investigations

A

IGF-1 measurement

oral glucose uptake to confirm if there is a raised IGF-1

MRI - assess tumour size

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5
Q

management

A

trans-sphenoidal surgery

somatostatin

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6
Q

why could the patient be sleepy

A

sleep apnoea

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7
Q

what type of MEN is it

A

MEN 1

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8
Q

what is a complication

A

cardiomyopathy

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