Acromegaly Flashcards
1
Q
acromegaly
A
excess GH secretion causing excess IGF-1
2
Q
causes
A
pituitary adenoma
ectopic GHRH tumours (small percent)
3
Q
signs
A
large feet, hands, mouth, nose sweating headaches day time sleepiness coarsening features pituitary adenoma features
4
Q
investigations
A
IGF-1 measurement
oral glucose uptake to confirm if there is a raised IGF-1
MRI - assess tumour size
5
Q
management
A
trans-sphenoidal surgery
somatostatin
6
Q
why could the patient be sleepy
A
sleep apnoea
7
Q
what type of MEN is it
A
MEN 1
8
Q
what is a complication
A
cardiomyopathy