Diabetes dosing Flashcards
Chlorpropamide
250mg PO QD, may increase by 50-125 mg at 3-5 day intervals.
Glipizide
5mg PO QD initially. Titrate in 2.5-5 mg increments every few days. Max dose: 40 mg/day
Glyburide
2.5-5mg PO QD. increase up to 2.5mg/day at weeky intervals. Max dose: 20mg/day
Glimeperide
1-2 mg PO QD, may increase 1-2 mg q 1-2 weeks. Max: 8mg/day
Metformin
500 mg BID, increased by 500 mg weekly until glycemic goals OR 2,000 mg/day
Pioglitazone
15-30 mg QD
Rosiglitazone
2-4 mg QD
Acarbose and Miglitol (dosing is the same)
25 mg with one meal a day, increase gradually over several months to a max of 50mg TID if < 60 kg, or 100mg TID if >60 kg.
Lantus and Levemir
Starting doses:
Type 1: .2-.4 U/kg
Type 2: 1 U per 20mg/dl above 100 fasting, 2 U per 20 mg/dl above 140 fasting
Humalog, Novolog, Apidra
1 U per 12-15 grams of carbs
Pramlintide
Type 1: 15 mcg prior to meals, can be titrated up in 15 mcg increments to a max of 60 mcg
Type 2: 60 mcg prior to meals, may be titrated to a max of 120 mcg.
Exenatide
5 mcg BID, titrated to 10 mcg BID in 1 month, or as tolerability allows.
Liraglutide
.6mg daily for >1 week, then 1.2 mg daily for > 1 week. pts may be maintained on the 1.2 mg dose or increased to the max 1.8 mg daily dose after > 1 week.
Sitagliptin (Januvia)
100 mg PO QD
Saxagliptin (Onglyza)
2.5-5 mg QD
Alogliptin (Nesina)
25 mg PO QD
Linagliptin (Tradjenta)
5 mg PO QD
Canagliflozin (Invokana)
100 mg PO QD, may increase to 300 mg PO QD
Colesevelam (Whelcol)
six 625 mg tablets daily. can be split into 3 tablets BID. Oral suspension packet also available.
Dulaglutide (Trulicity)
.75 mg SC once weekly
Max of 1.5 mg once weekly.
Albiglutide (Tanzuem)
30 mg SC once weekly, max 50 mg once weekly.
Dapaliflozin (Farxiga)
5 mg PO QAM w or w/o food, may increase to 10 mg PO QAM.
Bromocriptine mesylate
.8mg PO QD, may increase at weekly intervals in .8 mg incraments as tolerated. Usual dose: 1.6-4.8 mg/day.
