Diabetes Flashcards
metformin (Glucophage): Class
Biguanides - first line monotherapy
metformin (Glucophage): Use
Initial drug used to treat type II diabetes
metformin (Glucophage): EPA
Reduces the production of glucose by the liver, decreases absorption of glucose from the intestines & increases sensitivity of insulin receptors in tissues.
metformin (Glucophage): ADRs
Lactic acidosis, N/V/D, metallic taste, BLACK BOX WARNING
metformin (Glucophage): BLACK BOX WARNING
Risk for potentially fatal lactic acidosis for people with a history because increases production of lactate
metformin (Glucophage): contraindications
Not given during severe illness, surgery, or hospitalization
Pregnancy
Renal and hepatic impairment
Hx of lactic acidosis
ETOH
metformin (Glucophage): RN Interventions
take with meals, do not stop taking without consulting provider, avoid ETOH, CAN NOT be taken if client is having imaging done because it can cause kidney injury, hold 48 hrs before and after contrast imagery
glipizide (Glucotrol): Class
Sulfonylureas
glipizide (Glucotrol): Use
Used in combination with diet to lower blood sugar levels in patients with type II diabetes
glipizide (Glucotrol): EPA
Stimulates pancreatic beta cells to produce more insulin, therefore increasing secretion of insulin.
glipizide (Glucotrol): ADR
hypoglycemia
glipizide (Glucotrol): contraindications
Sulfa allergy-should not take
Pregnancy
Renal or hepatic dysfunction
glipizide (Glucotrol): RN Interventions
take 30 minutes before meals, Not given during severe illness, surgery, hospitalization or pregnancy (need to take insulin instead to control blood sugars)
repaglinide (Prandin): classification
Meglitinides
repaglinide (Prandin): EPA
similar to sulfonylureas, stimulate section of insulin
pioglitazone (Actos): Classification
Thiazolidinediones (TZDs)
pioglitazone (Actos): EPA
reduces insulin resistance of tissue
acarbose (Precose): Classification
Alpha-glucosidase inhibitors
acarbose (Precose): EPA
blocks/delays digestion/absorption of carbs
sitagliptin (Januvia): Classification
Gliptins