Dextrose 50%

Question 1

Brand

Class

Answer 1

Dextrose 50%
D50

Carbohydrate

Question 2

Mech of action

Answer 2

Raises blood sugar

Question 3

Indications

Contraindications

Answer 3

ALOC
Seizures
Known hypoglycemia

Stroke ( unless documented hypoglycemia)
Intracranial hemorrhage

Question 4

Adverse reaction

Answer 4

Cerebral edema and intracranial hemorrhage in children when given IV undiluted. Worsens elevated ICP, extravasation leads to severe tissues necrosis.

Question 5

Notes of administration

Answer 5

Use D10% for ped pt’s

Question 6

Adult dose

Ped dose

Answer 6

Hypoglycemia, ALOC, or seizures of unknown etiology:
25-50 ml or D50 (12.5-25Gm, 1/2 to 2 amps) IV

0.5-1gm/kg (5-10 cc/kg) of a dextrose 10% solution, recommended to five slowly over a 20 min period. (250 ml NS waste 50ml and add 50ml of D50 provides D10 or 10gm/ml)

Question 7

Route

Onset

Special notes

Answer 7

IV-IO (rapid)

Seconds

Determine a blood glucose level before initiating dextrose

Question 8

Dosage form

Answer 8

25 gms/50 ml prefilled syringe