Acetylsalicylic Acid Flashcards
Generic
Acetylsalicylic acid
Aspirin
ASA
Class
Analgesic
Antipyretic
Anti inflammatory
Mech of action
In small doses Aspirin blocks thromboxane A2
A potent platelet aggregate and vasoconstrictor
This property has led to its use in the acute phase of management of the MI
decreased platelet aggregation
Indications
Chest pain or other signs/symptoms suggestive of AMI
ECG changes suggestive of AMI
unstable angina
Pain, discomfort, fever in adult pt only
Adverse reaction
Use with caution in the pt with history of asthma
Anaphylactic reactions in sensitive pts have occurred;skin eruptions
Other side effects rare with single dose
Adult dose
Ped dose
Route
Onset
Cardiac 160-325mg
(2-4 pediatric chewable tabs, chew or swallow
Pain/discomfort/fever
325mg
Not recommended for pre hospital use in children
Oral
20-30 min
Special notes
Baby ASA is heat and light sensitive. Odor of acetic acid (vinegar like smell)indicates degradation of product
Contraindications
Bleeding ulcer, hemorrhagic states, hemophilia
Known hypersensitivity to salicylates or other non steroidal anti inflammatories that has lead to hypotension and or bronchospasm
Children and adolescents
Onset of action
20-30 min
Peak effects
Duration of action
2 hours
4-6 hours
Arizona drug box minimum supply
324
