Developmental aspects of Lung disease Flashcards
Abnormalities of growth and development of the lung are origins of whatt?
‘Adult’ Lung disease
What are the 5 stages of lung morphogenesis?
Embryonic Pseudo-glandular Canalicular Saccular Alveolar
During embryonic development, what is not possible?
Gas exchange is not possible
In which stage would you start to see myofibroblasts?
Pseudo-glandular
During which stage does life become possible?
The Canalicular stage
When does surfactant generally become apparent?
When life first becomes possible
When does the diaphragm develop?
The pseudo-glandular stage
During the first few breaths of the child, the lungs do what?
Change from a fluid secreting organ to a fluid absorbing one
The failure of the function of the lung following birth in a child can lead to what?
Wet Lung
What does surfactant do?
Stabilisies alveoli and promotes gas exchange
What is neonatal lung disease?
When there is no proper ventilation due to surfactant deficiency
How can neonatal lung disease be prevented?
With antenatal steroids
