Development of the Musculoskeletal system Flashcards

1
Q

When does the development of the musculoskeletal system begin

A

4th week

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2
Q

how long does the development of the musculoskeletal system last

A

through fetal period and even after birth

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3
Q

What does skeletal tissue arise from

A

mesenchyme (regions differ)

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4
Q

Arises from mesenchyme derived from the scolerotom portion or mesodermal somites

A

axial skeleton

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5
Q

Arise from mesenchyme derived from the lateral plate mesoderm

A

appendicular skeleton

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6
Q

pectoral girdle, pelvic girdle and limbs

A

appendicular skeleton

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7
Q

the axial skeleton is what in origin

A

segmented

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8
Q

The bones or the face and some of the bones covering the brain arise from

A

Neural crest cells

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9
Q

Other Cranial bones arise from

A

Mesoderm

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10
Q

Vertebral column, ribs and neurocranium mesenchyme arise form

A

paraxial mesoderm

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11
Q

pectoral girdle, pelvic girdle, limbs and sternum mesenchyme is developed from

A

lateral plate mesoderm

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12
Q

Viserocranium and hyoid mesenchyme is developed form

A

Neural crest cells

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13
Q

The roof and the base of the skull are developed from

A

paraxial mesoderm

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14
Q

Calvaria

A

Skull cap

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15
Q

Where are neural crest cells derived form

A

ectodermal origin

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16
Q

Anterolateral facial bones

A

Viserocranium

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17
Q

Bones encasing the brain

A

Nuerocranium

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18
Q

Nuerocranium is formed from what types of ossification

A

Membranous and cartilaginous

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19
Q

Neurocranium that is formed by cartilaginous ossification

A

base of the skull

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20
Q

Neurocranium that is formed by membranous ossification

A

Calvaria

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21
Q

Lesser wing of the sphenoid, petrous potion of the temporal bone, portions of the ethmoid and occipital bones

A

base fo the skull

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22
Q

membranous flexible joints of the skull in infants

A

sutures

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23
Q

enlarged membranous space where more than 2 bones meet

A

fontanelles

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24
Q

Area where the 2 parietal bones and frontal bones meet

A

anterior fontanelle

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25
Spinal nerves in the cervical region (does/ does not) match the number of vertebrae
Does not
26
Spinal nerves in the thoracic region (does/ does not) match the number of vertebrae
Does
27
Spinal nerves in the lumbar region (does/ does not) match the number of vertebrae
Does
28
Spinal nerves in the sacral region (does/ does not) match the number of vertebrae
Does
29
when the cells in the sclerotome split, the cells in the line of division coalesce
Annulus fibrosus
30
The Annulus fibrosus enclosed the notochord
nucleus pulposus
31
What happens the the notochord everywhere that it is not found in the Annulus fibrosus
degenerates
32
Grows out lateral extensions of the costal processes developing from the thoracic vertebrae
Ribs
33
lateral extensions of the costal processes developing from the thoracic vertebrae to form the ribs
Wrap anteriorly
34
development of the ribs is dependent on the development of the
vertebrae
35
What type of joints form where costal process meets the vertebrae
synovial
36
Mesenchyme in what region forms the ribs
costal
37
Induced to form by the ribs at the ventral midline
sternum
38
What type of tissue forms the sternum
Lateral plate SOMATIC mesoderm
39
Develops as 2 bars that with fuse cranial to caudal
Sternum
40
Part of the axial skeleton that is not formed from paraxial mesoderm
Sternum
41
Fusing of the sternal bars for the
cartilaginous model
42
Mesenchyme of the appendicular skeleton forms from the
lateral plate SOMATIC mesoderm
43
The bones of the appendicular skeleton forms from what type of ossification
endochondral
44
During the 5th week condensation of mesenchyme forms the
Limb buds
45
During the 6th week mesenchyme bone models undergo chondrification to form
Hyaline bone models
46
When is the cartilage model for limb bones complete?
8th week
47
All types of muscle are formed during
embryonic development
48
Muscle type(s) that is formed from paraxial mesoderm
Skeletal
49
Muscle type(s) that is formed from intraembryonic SPLANCHNIC mesoderm
Cardiac and smooth
50
Is all smooth muscle formed from intraembryonic SPLANCHNIC mesoderm
No
51
what form the smooth muscle of erector pili, blood vessels, etc
local mesenchyme
52
What are the somites formed from
paraxial mesoderm
53
what do the somites further divide into
Sclerotomes Myotomes Dermatomes
54
Derivative of somite that forms the axial skeleton
sclerotomes
55
Derivative of somite that forms skeletal muscle
Myotomes
56
Derivative of somite that forms the overlying dermis of the back
Dermatomes
57
Myotomes forming skeletal muscle reorganize into
Hypomeres and epimeres
58
At the same times that myotomes are reorganizing into Hypomeres and epimeres spinal nerves are separating into
Ventral and dorsal rami
59
Deep muscles of the back develop from
epaxial muscle (epimeres)
60
Deep muscles of the back are inverted by what rami
dorsal
61
The erector spinae group and transversospinalis groups are formed from
Epimeres
62
The erector spinae group and transversospinalis groups are form
deep muscles of the back
63
The rectus column and hypaxial muscles are formed from
hypomeres
64
The rectus column and hypaxial muscles are form the
limbs and body wall muscles
65
The muscles of the limbs and the body wall are inverted by what part of the spinal nerve
Ventral
66
Mesenchyme surrounding the heart tube develop into
Cardiac muscles
67
Mesenchyme surrounding the gut tube develop into
smooth muscle
68
Smooth muscle of the iris is developed form from
neuroectoderm
69
Smooth muscle of salivary and sweat glands form from
Surface ectoderm
70
The limb bud develops at the end of what week
4th
71
Which set of limbs develop first
upper
72
the second set of limbs appears how long after the first
1-2 days (lower limbs)
73
The limb bud develops
proximal to distal
74
during what time period does the limb formation occurs
4th-8th
75
Mass of mesenchyme covered by ectoderm
Limb bud
76
what type of mesoderm does the limb bud develop from initially
lateral plate somatic mesoderm
77
What types of cells migrate to invade the mesenchyme of the limb bud
Somite mesenchyme neural tube cells neural crest cells
78
The somite mesenchyme cells that migrate to the limb bud form
epithelial and muscles cells
79
The neural crest cells that migrate to the limb bud form
Melanocytes Schwann cells Sensory axons
80
The neural tube cells that migrate to the limb bud form
Motor axons
81
Thickening of ectoderm at the distal end of the limb bud
Apical ectodermal ridge (AER)
82
specialized, multilayer epithelial structure are th end of the limb bud
AER
83
the AER effect near by mesenchyme in what way
inductive influence
84
undifferentiated and rapidly dividing cells in the limb bud to form more tissue
progress zone
85
As the limb bud grows proximal to distal where are the older cells located
closer to the body
86
The distal end of the limb bud flattens to form what
hand and foot plates
87
Soon after the limb bud grows out what migrates into the area
muscle progenitors
88
What are the two types of the muscles progenitors
ventral and dorsal mass
89
The flexors, pronators, and adductors form from what muscles mass
Ventral
90
The extensors, supinators, and abductors form from what muscle mass
Dorsal
91
Limb rotation occurs during what week
7th
92
What type of rotation does the upper limb undergo
90 degrees laterals
93
What type of rotation does the lower limb undergo
90 degrees medial
94
How are the limb buds are initially positioned
straight forward
95
Mesenchyme condenses at the hand and foot plates to form
Digital rays
96
Mesenchyme in the digital ray outlines the area of the
future digits
97
At the tip of each a portion of the AER induces mesenchyme to develop into the primordial of the
bones of the digits
98
bones of the digits
Phalanges
99
Intervals between the digital rays is occupied by
Loose mesenchyme
100
How are the notches of the digital rays formed
Apoptosis
101
Mesenchyme of the digital ray differentiate into hyaline cartilage due to
AER induction
102
Limb anomaly which results in absence of part of a limb
Meromelia
103
Limb anomaly which results in total loss of a limb
Amelia
104
Limb anomaly which results in an extra digit (supernumerary)
Polydactyly
105
Limb anomaly which results in 2 or more digits fused
Syndactyly