Cartilage Histology Articulate Flashcards
General composition of connective tissue
cells + ECM
What is the major competent of connective tissue: cells or ECM
ECM
What gives each connective tissue type their different characteristics
arragement of ECM
ECM is composed of
Protein fibers and ground substance
Types of protein fibers in the ECM
Collagen
Reticular
Elastic
made up of Glycosaminoglycans (GAGs), Proteoglycans, and iadhesive Glycoproteins
Ground substance
hyaluronic acid and chondroitin sulfate
Glycosaminoglycans (GAGs)
laminin and fibronectin
Multiadhesive Glycoproteins
Can be fluid, semifluid, gelatinous, or calcified
Ground substance
All connective tissues are derived from the loosely organized embryonic connective tissue known as
Mesenchyme
Mesenchyme is considered to be
multipotent
what type of tissue is blood
connective
Mesenchymal cells differentiate into _____ which are cells associated with developing cartilaginous tissue
chondroblasts
Is Cartilage vascularized
No
Growth by addition to an existing surface; generation of new chondroblasts
Appositional Growth
Growth by internal expansion; proliferation of chondrocytes and formation of isogenous groups
Interstitial Growth
Mechanisms of Cartilage Growth
Interstitial & Appositional
Role is to secrete extracellular matrix
chondroblast
Role is to secrete and maintain the extracellular matrix
chondrocyte
Are found in cavities within the extracellular matrix called lacunae
chondrocyte
What percent of cartilage is the extracellular matrix
~95%
Tissue that is resilient to external pressures and has high tensile strength
Cartilage
Tissue capsule that covers most, but not all, cartilages called
perichondrium
perichondrium is made of what type of tissue
dense connective tissue
contains blood vessels, nerves, chondrogenic cells, fibroblasts, and type I collagen fibers
perichondrium
essential for the growth and maintenance of the cartilage
perichondrium
Receive nutrients and oxygen via diffusion from blood vessels located in the perichondrium
chondrocytes in lacunae
What limits the growth of cartilage?
limited diffusion of ECM
Hyaline Cartilage, Elastic Cartilage, and Fibrocartilage are what
types of cartilage
The most common type of cartilage in the human body
Hyaline cartilage