Development of the Great Vessels Flashcards
what helps with vessel repair?
angiogenesis
what do aortic arches arise from
aortic sac (appear cranial->caudal), not simultaneously
- terminate in the R and L dorsal aorta
- begin appearing around week 4
arch I derivatives
maxillary a
arch II derivatives
stapedial a (middle ear)
arch III derivatives
common, int, and ext carotid a
arch IV derivatives
L: part of aortic arch
R: prox portion of subclavian
arch VI derivatives
L: L pulm a and ductus arteriosus (shunts blood from pulm vasc to aortic vasc)
R: R pulm a
arch VII derivatives
L: L subclavian a
R: R distal portion of subclavian a
what is the L horn of aortic sac
prox portion of aortic a
when are all great vessels developed and assembled by
week 8
path of R and L recurrent laryngeal nn
R: loops under R subclavian
L: loops under arch of aorta
what do most somatic aa of trunk develop from
intersegmental aa from dorsal aa
- develop 1. intercostal aa
2. lumbar aa
vitelline a
- initially are number if paired vessels supplying the yolk sac and initiate there
- develop 1. cilia a (tr) 2. superior mesenteric a
umbilical a
- initially paired ventral brs off dorsal aorta, course to placenta from embryo
- develops 1. inf mesenteric a 2. forms secondary connection with dorsal aorta->common iliac a
coronary aa
derived from epicardium
-connection to aorta is formed by ingrowth of arterial endothelial cells
embryonic venous system
3 pairs of major vv
- vitelline vv: drains GI tract and gut derivatives
- umbilical vv: oxygenated blood from placenta to embryo
- cardinal vv: draining head, neck, and body wall
vitelline vv
- forms plexus around duodenum and pass thru septum transversum before entering sinus venosus
- liver chords growing into septum interrupt the course and form hepatic sinusoids
- network around duodenum wall form a single vessle->hepatic portal v
what happens when the L sinus horn reduces
- rechannels blood from L side of liver to R
- R vitelline duct enlarges (forms part of IVC, sup mesenteric v)
- R-L anastamoses remodel to drain into portal v as splenic v and inf mesenteric v
umbilical vv
-R will regress and obliterate
L witll lose connection to sinus horn and form ductus venosus (bypass sinusoidal plexus of the liver, drain blood directly into the IVC)
cardinal vv
- drains embryo “proper”
- consists of ant (drains cephalic pt), post (drains rest of embryo), and common cardinal vv
what supplements and then replaces post cardinal vv
sub/supracardinal vv
what does caudal remnant of post cardinal vv develop into
common iliac v and sacral portion of IVC
ant cardinal vv
- cranial portions give rise to IJVs
- capillary plexus in face rise to EJVs
- forms brachiocephalic vv
- sup vena cava formed by R common cardinal and prox portion of R ant cardinal
abdominal portion of supracardinal vv
- inf portion of L obliterates
- R and subcardinal anastamose to form a segment of IJV
thoracic portion of supracardinal vv
L thor supracardinal = hemiazygos v
-remaining portion of inf R supracard drains to heart (azygos v)
subcardinal vv
- forms renal vv and gonadal vv
- longitudinal segments of L regress after forming anastamoses
- R forms portion of renal segment of IVC
6 primary lymphatic sacs
2 jugular
2 iliac
1 retroperitoneal
1 cisterna chyli
development of lymphatic system
- vessels will connect to the sac and pass along main vv
- R and L thoracic ducts initially connect the jugular sacs with cisterna chyli
- thoracic duct = caudal R lymphatic duct and anastamosis of R and L cranial thor ducts
- R lymphatic duct = cranial portion of the R thor duct
