Development of Heart Flashcards
Cardiogenic area - Derived from
Splanchnopleuric layer of lateral mesoderm.
Location of Cardiogenic area
Cranial to oropharyngeal membrane
Angioblastic cells gives rise to
Heart tubes
Heart tubes are derived from
Angioblastic cells
Single Heart tube is formed on
D19
Parts of Heart tube
Bulbus cordis
Primitive Ventricle
Primitive atrium
Sinus venosus
Bulbus cordis - Parts
Truncus arteriosus - Outflow tract of Aorta and Pulm. Trunk.
Conus - Spiral septum
Proximal 1/3rd - Rough part of RV
Truncus arteriosus gives rise to
Outflow tract of Aorta and Pulm. Trunk.
Proximal 1/3rd of Bulbus cordis gives rise to
Rough part of RV
Rough part of RV derived from
Proximal 1/3rd of Bulbus cordis
Primitive ventricle gives rise to
Rough part of LV
Primitive atria gives rise to
Rough part of RA and LA
Rough part of RA and LA derived from
Primitive atria
Smooth part of RA derived from
Body and Rt horn of Sinus venosus.
Smooth part of LA derived from
Absorption of Pul veins.
Absorption of Pul veins gives rise to
Smooth part of LA
3 veins of horn’s of Sinus venosus
Umbilical vein, Vitelline vein and Common cardiac vein.
Coronary sinus is formed by
Lt horn of Sinus venosus
What happens to Lt horn of sinus venosus.
Obliterates and forms coronary sinus.
Conotruncal septum aka
Spiral septum or Aorticopulmonary septum
Conotruncal septum is derived from
NCC
Spiral septum - fxn
divides truncus arteriosus in a way that pul trunk goes into RV and aorta into LV.
Anterior Displacement of Spiral septum causes
TOF
TOF - Features
Pulmonary stenosis.
Overriding aorta.
RV hypertrophy.
VSD.
TOF cause -
Antr displacement of Spiral septum.
Non - Spiral Septum causes
TGV
TGV causes
Non spiralling of septum.
Persistent Truncus arteriosus causes
Failure of migration of NCC.
EGG on string appearance is seen in
TGV
Ostium primum is between
Septum primum and AV cushion
Gap btw AV cushion and Septum primum is
Ostium primum.
Gap btw Septum secundum and septum primum
Foramen ovale.
What causes fusion of Septum primum and secundum
Inc in pressure of LV at time of birth
Remnant of Septum primum
Fossa ovalis
Remnant of Septum secundum
Limbus fossa ovalis.
Parts of Interventricular septum
Muscular part
Membranous part
Outflow / Infundibular part.
Muscular part of IVS derived from
Myocardium
Membranous part of IVS derived from
ECC
ECC gives rise to
Atrial septa and Ventricular septa
AV canals
AV valves
Aortic and pulmonary channels.
Outflow /infundibular part of IVS derived from
NCC.
NCC derivatives of CVS
Outflow or infundibular IVS and Conotruncal septum.