Development of Face and Palate

Question 1

When does development of the face happen?

Answer 1

4-8 weeks in utero

Question 2

When does formation of the palate happen?

Answer 2

6-10 weeks in utero

Question 3

When is the earliest bone laid down in the skull?

Answer 3

6/7 weeks mandible

Question 4

What are the pharygeal arches?

Answer 4

4/6 ridges that are precursors for parts of the face/skull

Question 5

What develops from the 1st arch?

*hint - ear

Answer 5

trigeminal nerve
mom
malleus
incus
meckel’s cartilage

Question 6

What are the 5 prominences?

Answer 6

Frontonasal
paired maxillary
paired mandibular

Question 7

What do the paired prominences develop from?

Answer 7

1st pharyngeal arch

Question 8

What does the frontonasal prominence develop from?

Answer 8

overlies developing forebrain

Question 9

What processes form the intermaxillary process and what does this give rise to?

Answer 9

Medial nasal (frontonasal) processes form intermaxillary process - gives rise to philtrum of lip and primary palate

Question 10

What do the maxillary prominences give rise to?

Answer 10

lateral palatal shelves (secondary palate)

Question 11

Primary vs Secondary palate

Answer 11

Primary - Gives rise to the premaxilla bone and the anterior portion of the hard palate

Secondary - Gives rise to the majority of the hard palate and soft palate posterior to the incisive fossa

Question 12

What is the frontonasal prominence?

Answer 12

forehead

Question 13

Why is meckel’s cartilage important?

Answer 13

mandible forms around this cartiage (serves as a template that guides osstification process around it)
part of inner ear bone forms from this cartilage (malleus)

Question 14

What is cleft lip due to?

Answer 14

failure of fusion between maxillary promience with the mesial nasial processes - can be unilateral or bilateral (extending to incisive foramen)

Question 15

What is cleft palate due to?

Answer 15

failure of two palatal shelves to fuse in the midline