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Oral Biology 2 > Development of Enamel 1 > Flashcards

Development of Enamel 1 Flashcards

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1
Q

Mature Enamel Properties

A

Non vascular

Acellular

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2
Q

What helps Enamel since its so brittle?

A

Underlying dentin for support

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3
Q

Explain thicknesses of Enamel

A

Thicker at crown

Thin at cervical line

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4
Q

Enamel percentage composition by WEIGHT

A

96% Inorganic
3% Water
1% Organic

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5
Q

What are the major enamel proteins

A

1) Amelogenins
2) Ameloblastins
3) Enamelin
4) Tuftelin

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6
Q

Mineral Components of enamel

2

A

Hydroxyapatite

Carbonatoapatite

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7
Q

Carbonate can substitute for what in namel?

A

Both Phospahte AND OH(sometimes)

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8
Q

Hydroxyapatite can incorporate what odd metal?

A

Magnesium

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9
Q

Carbonate and Magnesium are incorporated where in enamel?

A

Inner. Fluoride more outer

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10
Q

Does enamel crystals run entire length of ename layer?

A

Yes

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11
Q

enamel Rod def

A

Cylindrical accumulation of enamel crystals lined up along long axis of tooth

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12
Q

In what direction do rods run in respect to DEJ

A

Perpendicular

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13
Q

Are rods same as prisms?

A

Nope. Prism is more geometric

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14
Q

How are enamel rods organized?

A

Into rods that run in alternating directions

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15
Q

How many rods can 1 ameloblast make?

A

1 rod

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16
Q

What are the 2 rod sheath proteins

A

Ameloblastins

Amelogenins

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17
Q

What enamel component is much more prevalent in mammals than rodents

A

Rod sheath

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18
Q

Caries are thought to penetrate where in enamel composition

A

Rod sheaths

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19
Q

After the Inner Enamel Epithelium is formed, what is the stimullus for enamel to be formed?

A

Formation of pre-dentin by odontoblasts

20
Q

Ameloblast maturation has 3 phases

A

1) Pre-Secretory
2) Secretory
3) Maturation

21
Q

What happens duringPresecretory phase

A

Mature from pre-ameloblasts to ameloblasts

22
Q

What happens durng secretory phase

A

Deposition of enamel

23
Q

What happens durng Maturation

A

1) Reduction of organic matrix

2) Increase mineralization via ion transport

24
Q

Enamel is laid down in apposition to what?

A

To pre-dentin/mantle (first) dentin

25
Q

In what formation and held by what do the ameloblasts lay dentin?

A

Ameloblasts held together by Junctional complexes (terminal bars) move in sync to minimize gaps

26
Q

The initial ename laid due to apposition of dentin has what arrangement?

A

Uniform arrangement. Not rod arrangement

27
Q

Effectively what forms the enamel rod structure?

A

Tomes Process

28
Q

Tomes process proximal faces what?

A

Stratum intermedium

29
Q

Distal TOmes process faces what?

A

The forming enamel

30
Q

Interrod enamel and enamel rods come from what parts of tomes process?

A

Different parts

31
Q

What enamel is laid first by Tomes Process

A

Interrod

32
Q

Whats the process of laying enamel by Tomes Process

A

Interrod laid. It forms groove

Rod enamel laid in groove. Small gap around 3/4 of process fills with organic material and it forms the rod sheath

33
Q

Explain the culmination process of enamel deposition

A

Tomes Process retracts

Outer rods are straighter and outermost enamel is made without rods

34
Q

After enamel has been laid what happens to ameloblasts?

A

They become a squat cell (just lke a pre-ameloblast)

35
Q

After enamel has been laid what happens to tooth?

A

Loss of Stellate Reticulum
Fuson of OEE and IEE
The fusion results in a single layer of Reduced Enamel Epithelium

36
Q

What happens prior to eruption

A

Enamel hardens by removal of water and organic material

37
Q

How long does the pre-eruption hardening take

A

5 years. ABout 2/3 of amelogenesis is maturation

38
Q

After pre-eruption hardening what happens?

A

Production of basal Lamina at external enamel surface (not COllagen IV)
Then Modulation

39
Q

What happens f basal lamina is disrupted?

A

Enamel Hypoplasia

40
Q

Modulation def

A

Process by which water and proteins are removed

41
Q

Ruffled cells

A

Infiltration of Calcium Ions into crystals

42
Q

Smooth cells do what

A

Allow diffusion of protein fragments out of enamel

43
Q

What happens to the enamel organ after ename maturation

A

Fuses to form REE
Remnants fuse with oral epithelium forming covering for tooth. This forms a canal. This epithelial layer becomes the Dentogingival Junction

44
Q

Nasmyth’s membrane def

A

layer of remaining debris on crown of tooth

45
Q

Primary Enamel cuticle def

A

Last secretory product of amelobalsts

46
Q

Secondary Enamel Cuticle aka

A

Dental Cuticle

47
Q

Secondary Enamel Cuticle def

A

Formed from remins of REE merged with Oral epithelium and removed by mechanical forces

Oral Biology 2 (8 decks)

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