Development

Question 1

SHH

Answer 1

limbs – polarizing activity. AP patterning. CNS development. mutx–> holoprosencephaly

Question 2

WNT-7

Answer 2

D-V organization. produced at end of developing limb

Question 3

FGF

Answer 3

stimulates underlying mesoderm, lengthening of limbs

Question 4

Day 0

Answer 4

fertilization, forming zygote

Question 5

hCG secretion begins

Answer 5

within 1 week, after implantation of blastocyst

Question 6

during week 2

Answer 6

bilaminar disc (epiblast, hypoblast)

Question 7

week 3

Answer 7

trilaminar disc (gastrulation).
primitive streak, notocord, mesoderm, neural plate form

Question 8

organognesis

Answer 8

Weeks 3-8

Most susceptible to teratogens

Question 9

Neural tube closure

Answer 9

by week 4

Question 10

Heart begins to beat

Answer 10

week 4

Question 11

formation of limbs

Answer 11

week 4

Question 12

fetal period

Answer 12

starts in week 8

initiation of movement

Question 13

male/female genitalia

Answer 13

week 10

Question 14

12 months

Answer 14

• stands, walks first steps, throws ball
• 2 finger pincer
• first words (other than mama/dada)
• separation anxiety, follows 1-step command with gesture

Question 15

18 months

Answer 15

• runs, kicks ball
• builds tower of 2-4 clothes, removes clothing
• 10-25 word vocab, identifies >1 body part
• understands “mine”. pretend play

Question 16

2 years

Answer 16

• walks up/down stairs with both feet on each step. jumps.
• builds 6-cube tower, copies a line, turns pages
• 50+ word vocab. 2-word phrases
• 2 step command, parallel play, toilet training begins

Question 17

3 years

Answer 17

• up/down stairs with one foot on each step. tricycle
• copies circle, uses utensils.
• 3 word sentences. speech 75% intelligible.
• knows age/gender, imaginative play

Question 18

4 years

Answer 18

• balances and hops on 1 food
• copies a square
• identifies colors, speech 100% intelligible
• cooperative play

Question 19

5 years

Answer 19

• skips, walks backward
• copies a triangle, ties shoelaces, independent dressing/bathing, prints letters
• counts to 10. 5-word sentences
• has friends, completes toilet trainings