Development Flashcards
What is vasculogenesis?
Development of new blood vessels
What is angiogenesis?
Process where existing blood vessels length or branch by sprouting, continues postnatally
Where does blood and vessel development first begin before development begins in the embryo?
Extra-embryonically aka from the mother
What are ‘blood islands’?
Clusters of splanchnic mesoderm that lines the yolk sac
(T/F) Hemangioblasts are lineage committed
True
(T/F) Fetal hemoglobin is structurally the same as adult hemoglobin.
False
What do the angiogenic cell clusters in the cardiogenic plate give rise to?
Endocardial tubes
The cephalocaudal fold brings the heart dorsal or ventral to the pericardium?
Dorsal
Listed below are the different linings/layers of the developing heart, give the structure they become postnatally.
- Endothelial lining →
- Myoepicardial layer →
- Visceral layer lining the pericardial cavity →
- Endothelial lining → (Endocardium) - - - Myoepicardial layer → (Myocardium)
- Visceral layer lining the pericardial cavity → (Epicardium)
Why does the primitive heart go from a long tubular structure to a ‘S-shaped’ bent structure?
It is outgrowing the pericardial cavity
*What structures extend towards each other and fuse to create the left and right atrioventricular openings?
The endocardial ‘cushions’
What is the resulting anatomical structure of trabeculation (the process in which the heart grows without encroaching on the the luminal space of the ventricles, a balance between thickening of the heart walls and apoptosis of the endocardium) in the adult heart?
Trabeculae carneae
Why is pressure high in the right ventricle of the fetal heart?
Fetal lungs are not yet inflated
What is the name for the foramen that persists in the second atrial divider in the fetal heart?
Foramen ovale
What structures fuse in a twisting pattern to separate the common outflow tract of the fetal ventricles into two separate tracts, each serving one ventricle?
Trucoconal ridges
What does the 4th arches of the fetal aorta form?
Right → right subclavian; left → aortic arch
What does the 6th arches of the fetal aorta form?
Right → proximal pulmonary artery; left → ductus arteriosus
(T/F) Developmental cardiac anomalies are one the most common congenital defects faced by a general practitioner.
True
Is the incidence of congenital cardiac anomalies higher or lower in purebred dogs?
Higher
What does cyanosis result from?
Inadequate oxygenation of blood