desquamative gingivitis

Question 1

what is desquamative gingivitis?

Answer 1

not a specific disease but a response that includes intense erythema, desquamation, and ulceration of the free and attached gingiva

Question 2

how can you diagnose desquamative gingivitis?

Answer 2

biopsy, microscopic exam, immunofluorescence

Question 3

to reach a definitive diagnosis you need what 5 steps?

Answer 3

clinical history, clinical exam, biopsy, definitive diagnosis, management.

Question 4

lichen planus

Answer 4

is an immunologocal mediated mucocutaneous disorder which utilizes T lymphocytes

Question 5

is lichen planus premalignant?

Answer 5

yes!

Question 6

female to male ration of OLP( oral lichen planus)

Answer 6

2:1

Question 7

where are the oral lesions found in OLP?

Answer 7

posterior buccal mucosa

Question 8

OLP can cause keratotic lesions, ulcerative lesions, bullous and atrophic lesions, and the most common which is……..

Answer 8

erosive reticular lesions

Question 9

using direct immunofluorescence, where would they attach?

Answer 9

linear fibrilar deposits of fibrin in the BM

Question 10

how are keratotic lesions treated?

Answer 10

their not, all you can do is follow ups

Question 11

how are symptomatic lesions treated?

Answer 11

fluocinonide ointment, triamcinolone acetonide injection, prednisone

Question 12

whats pemphigoid?

Answer 12

immune mediated subepithelial bullous disease

Question 13

how is bullous pemphigoid detected?

Answer 13

direct and indirect immunofleorescence

Question 14

what does cicatricial pemphigoid involve?

Answer 14

oral cavity , conjuctiva, and mucosa

20% of the time it involves the skin

Question 15

whats happening with the connective tissue and epithelium in cicatricial pemphigoid?

Answer 15

they are separating and forming subepithelial vesicles

Question 16

how can you treat cicatricial pemphigoid?

Answer 16

topical steroids, systemic steroids, referr to dermatologist

Question 17

what are pemphigus disorders?

Answer 17

group of autoimmune bullous disorrders with cutaneous and or mucous membrane blisters

Question 18

whats the mortality rate of pemphigus vulgaris?

Answer 18

10%

Question 19

what areas are involved with pemphigus vulgaris?

Answer 19

soft palate, buccal mucosa, dorsum of tongue, lower labial mucosa
60% of time in ivolves the skin within a year

Question 20

whats the histopathalogy of pemphigus vulgaris?

Answer 20

intraepithelial separation above basal cell layer, acantholysis, large hyperchromatic nuclei, tzanc cells

Question 21

how do you treat pemphigus vulgaris?

Answer 21

system corticosteroids.