Describe the relationship between a protein’s shape and its function Flashcards
Why is a protein’s shape crucial to its function?
A protein’s shape determines how it interacts with other molecules, directly affecting its ability to perform its specific function.
What happens to a protein’s function if its shape is altered?
If a protein’s shape is altered (denatured), it may lose its ability to function properly because it can no longer interact with other molecules in the same way.
How does the sequence of amino acids in a protein affect its shape?
The sequence of amino acids determines how the protein folds into its specific 3D shape, which is essential for its function.
What is the relationship between enzyme shape and substrate specificity?
The shape of an enzyme’s active site is complementary to the shape of its specific substrate, allowing the enzyme to bind to the substrate and catalyze a reaction.
How can changes in pH or temperature affect a protein’s shape?
Changes in pH or temperature can cause a protein to denature, losing its shape and, consequently, its ability to function.
What is meant by “protein folding,” and why is it important?
Protein folding is the process by which a protein assumes its functional 3D shape. Proper folding is crucial for the protein to perform its specific function.
How do chaperone proteins assist in protein function?
Chaperone proteins help other proteins fold into their correct shapes, ensuring they achieve the proper structure to function correctly.
Can a protein have more than one functional shape?
Yes, some proteins can change shape in response to environmental factors, allowing them to perform different functions in different conditions.
What role does protein shape play in disease?
Misfolded proteins can lead to diseases, such as Alzheimer’s or Parkinson’s, where the altered shape impairs normal protein function or causes harmful aggregates.
What is the significance of a protein’s tertiary structure?
The tertiary structure is the overall 3D shape of a protein, crucial for its interaction with other molecules and its ability to perform its function.
What are the two main ways a protein folds
- Alpha Helix
- Beta-Pleated Sheet
