Descending pathways Flashcards

1
Q

where do upper motor neurones originate

A

1st order neurones in the cerebrum and the subcortical structures

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2
Q

where do lower motor ebonies originate from

A

originate and have their cell bodies in the brain stem and spinal cord (ventral grey horn)

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3
Q

what are the three descending pathways

A

corticospinal - from cortex to spinal cord which initiates movement - body muscles

corticonucelar - from cortex to brainstem - control facial muscles and initiate movement

extrapyramidal - 3 different tracts which modify and coordinate movement

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4
Q

what is the general route of the corticospinal/nucelar pathway

A

cerebral cortex to precentral gyrus to internal capsule to brainstem / spinal cord

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5
Q

what is the nerve difference between the corticonucelar and spinal tracts

A

nuclear - cranial nerves

spinal - spinal nerves

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6
Q

what are the locations of the descending fibres in the midbrain, pons and medulla

A

midbrain - cerebral peduncles (crus cerebri)

pons - ventral pons as fascicles

medulla - pyramids

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7
Q

which of the nucelar/spinal descending pathways cross the midline

A

corticospinal decussate at the pyramids but corticonucelar does not

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8
Q

what are the 6 steps in the corticospianl tract

A
cerebral cortex 
internal capsule 
crus cerebrii
ventral pons
open medulla (rostral pyramids)
crossing at the decussation of pyramids in the closed medulla
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9
Q

what happens to the cortospianl tract after the decussation of pyramids and what does this mean

A

85% fibres cross and enter the lateral corticospinal tract (contralateral)

15% don’t cross and enter the anterior corticospinal tract (ipsilateral)

bilateral innervation

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10
Q

what is the somatotropin organisation of the lateral corticospinal tract and what is its role

A

neurones for the leg are lateral and for the arm medial
leave through ventral grey horn for limb musculature

attach to lower motor neurones on the same side

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11
Q

what is the role of the anterior corticospinal tract

A

contact lower motor on both sides (both ventral grey horns) for axial musculature (bilateral innervation)

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12
Q

what is the main method of innervation of LMN’s for the corticonucelar pathway and give an example

A

bilateral except for the lower facial and extrinsic tongue muscles which are under contralateral control

hypoglossal nerve = contralateral central

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13
Q

what is the corticonucelar input to facial motor nuclei

A

bilateral input to facial nucelli in the pons via internal capsule

upper face = LMN’s from both nuclei

lower face LMNs from the ipsilateral facial nuclei which receives input fromm the centrallatersal cortex

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14
Q

how can lower motor neurone damage occur and where does it occur

A

injury to ventral grey horn or axon as it leaves the spinal cord
may be due to poliomyelitis - acute viral infection of neurone - muscle wasting

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15
Q

what would an LMN lesion of descending motor pathway cause at the level of the lesion

A

hyporeflexia or areflexia

muscle wasting, weakness hypotonia

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16
Q

which locations can you get UMN lesions

A

cerebral cortex, brainstem, spinal cord

17
Q

what would an UMN lesion of motor pathways result in for limbs short term and long term

A

flaccid paralysis of opposite limbs and loss of tendon reflexes

long term hyperflexia (always contracted muscle)
loss of motor control

18
Q

what is a silver lining of UMN lesion for motor pathways

A

axial muscles spared due to bilateral innervation

19
Q

what are the three extrapyramydial pathways and what do they do

A

reticulospinal pathway - reticular formation (pons and medulla to spinal cord - assists voluntary movement breathing and consciousness)

vestibulospianl pathway - vestibular nuclei - pons and costal medulla to spinal cord - controls posture

rubrospinal - red nucleus (midbrain to spinal cord) controls muscle tone