Dermatophytoses: Tinea Unguium Flashcards
Tinea Unguium Synonym
Onychomycosis)
Tinea Unguium Clinical Feature
Crumbling, distally dystrophic nails; yellowish, opaque
with subungual hyperkeratotic debris
Toenail infections usually precede fingernail infections
Tinea Unguium Etiology
T. rubrum (90% of all toenail infections)
Tinea Unguium Diff Dx
Psoriasis, lichen planus, contact dermatitis, traumatic onychodystrophies, bacterial infection
Tinea Unguium Investigations
Microscopic examinations of KOH prep of scales from
subungual scraping shows hyphae
Culture of subungual scraping or nail clippings on Sabouraud’s agar
PAS stain of nail clipping by pathology
Tinea Unguium Management. First line
Terbinafine (Lamisil®) (6 wk for fingernails, 12 wk for toenails) Itraconazole (Sporanox®) 7 d on, 3 wk off (2 pulses for fingernails, 3 pulses for toenails)
Tinea Unguium Management Adjunctive
Topical: ciclopirox (Penlac®);
nail lacquer (often ineffective),
Efinaconazole (Jublia®) (48 wk)