ALOPECIA AREATA Flashcards
Alopecia Areate. Pathophysiology and clicical feature+ area
autoimmune disorder characterized by patches of complete hair loss often localized to scalp, but can affect eyebrows, beard, eyelashes, etc.
Alopecia Areata. Associated nails alterations
may be associated with dystrophic nail changes – fine stippling, pitting
Alopecia Areate. Hair Pattern
“exclamation mark” pattern (hairs fractured and have tapered shafts, i.e. looks like “!”)
Alopecia Areata. Associated systemic alterations
may be associated with pernicious anemia, vitiligo, thyroid disease, Addison’s disease
Alopecia Areate. Regrowth
spontaneous regrowth may occur within months of first attack (worse prognosis if young at age of onset
and extensive loss)
Alopecia Areata. Recurrence?
frequent recurrence often precipitated by emotional distress
Alopecia Areate. alopecia totalis:
complete loss of hair on scalp
Alopecia Areata. alopecia universalis:
complete loss of scalp hair, eyelashes, eyebrows, and body hair
Alopecia Areate. can there be a good prognosis?
excellent prognosis for localized disease
Alopecia Areate. Local treatment
topical corticosteroids and intralesional triamcinolone acetonide (corticosteroids) can be used for isolated patches
Alopecia Areata. management in severe cases
systemic immunosuppressants for refractory or extensive disease
• immunomodulatory (diphencyprone, anthralin)