Angioedema

Question 1

Angioedema Clinical feature, symptoms

Answer 1

deeper swelling of the skin involving subcutaneous tissues; often involves the eyes, lips, and tongue
• may or may not accompany urticaria

Question 2

hereditary angioedema. Comes with urticaria?

Answer 2

no

Question 3

hereditary angioedema Onset

Answer 3

in childhood; 80% have positive family history

Question 4

hereditary angioedema, presentation and mortality

Answer 4

recurrent attacks;; 25% die from laryngeal edema

Question 5

hereditary angioedema triggers

Answer 5

minor trauma, emotional upset, temperature changes

Question 6

• types of acquired angioedema

Answer 6

■ acute allergic angioedema (allergens include food, drugs, contrast media, insect venom, latex)
■ non-allergic drug reaction (drugs include ACEI)
■ acquired C1 inhibitor deficiency

Question 7

angioedema treatment

Answer 7

■ prophylaxis with danazol or stanozolol for hereditary angioedema
■ epinephrine pen to temporize until patient reaches hospital in acute attack