Dermatomyositis Flashcards

1
Q

What?

A

Polymyositis with additional typical cutaneous features

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2
Q

Typical features?

A

Gottron’s sign
Hellotrope rash
Shawl sign

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3
Q

Gottron’s sign?

A

Reddish/ purplish discolouration of PIP and DIP joints

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4
Q

Hellotrope rash?

A

Similar to Gottrons but around the eyes

Eye swelling

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5
Q

Shawl sign?

A

Reddish/ purplish rash on back of shoulder & front of chest

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6
Q

Examination?

A

Look at muscles -> wasting?
Skin involvement> - for dermatomyositis
Test muscle power – confrontational testing, isotonic testing

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7
Q

Investigations?

A
Raised inflammatory markers
Raised serum CK levels
Autoantibodies
MRI
EMG
Muscle biopsy
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8
Q

Autoantibodies?

A

ANA, anti- Jo- 1, anti- SRP

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9
Q

Definitive investigation?

A

Muscle biopsy

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10
Q

Management?

A

Prednisolone (40mg) with immunosuppressive drug (methotrexate or azathioprine)

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11
Q

What is this associated with?

A

Malignant (must be screened for once diagnosed)

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