Dermatology

Question 1

Most common form of skin CA

Answer 1

Basal cell CA-

Pearly, red papules or plaques with Rolled borders and Telangiectasias

sun exposed areas

Question 2

Langerhans cells (can exit epidermis to travel to lymph nodes and present antigens) play a prominent role in

Answer 2

Allergic contact dermatitis, like

Poison ivy

Question 3

Merkel cells

Answer 3

associated with touch, found more densely in touch-sensitive areas

discrimination of fine spatial details

Question 4

Merkel cell Carcinoma

Answer 4

Rare, aggressive form of skin CA

Deep pink or Red nodule, may mimic a furuncle or inflamed cyst

Question 5

Dermis includes:

Answer 5

• Support
• Collagen
• Elastic fibers
• Blood vessels
• Lymph vessels
• Nerves
• Glands
• Hair follicles

Question 6

Apocrine glands found ONLY in

Answer 6

Axillary
Anogenital areas

These glands open DIRECTLY into hair follicle

Question 7

Eccrine sweat glands

Answer 7

do NOT INVOLVE hair follicle.

Instead, open directly onto the skin

Present throughout body surface

Question 8

Function of Eccrine sweat glands

all over body, open directly onto skin

Answer 8

Regulate body temp

Question 9

Fibroblasts (resp for keloids, scarring) and Mast cells are found in the:

Answer 9

Dermis

Question 10

Function of Subcutis

Answer 10

Fat layer that separates dermis from Underlying fascia and muscles

made of: Adipocytes and Connective tissue

Fx:
insulation, energy supply, cushion/protect skin, allow for skin’s mobility

Question 11

If person is missing subcutis

Answer 11

Skin may be bound down, contractures to some limbs

Question 12

Erythema Nodosum (a disorder of the Subcutis)

Answer 12

inflammation of subcutis. Appears as deep-seated red nodules, often on shins

Assoc w: GI infections, Sarcoidosis, Crohn’s dz

Question 13

Epidermis (4 layers) from base up

Answer 13

Basal
Spinous
Granular
Corneum (top)

Question 14

Common tx for Atopic Dermatitis and Psoriasis

Answer 14

Topical Steroid

Question 15

Super high potency steroid

Answer 15

Class I

Question 16

Steroids within any class are equal in strength

Answer 16

Strength is based on the molecule, not the concentration

Question 17

Super high strength Steroid

Answer 17

Clobetasol propionate cream

Question 18

Medium strength steroid

Answer 18

Mometasone

Triamcinolone

Question 19

Low strength steroid

Answer 19

Desonide

Hydrocortisone

Question 20

When deciding on the strength of a steroid, what is more important to look at?

Answer 20

CLASS

not the %
Class I is strongest, Class VII is weakest

Question 21

Class I steroids are used for:

Answer 21

Scalp, palm, sole, thick plaque on extensor surface

Question 22

Med-high potency, Class 2-5 steroids are used for

Answer 22

Mild-mod NONFACE and NONintergriginous areas

Question 23

Low potency steroids (Class 6-7) are used for

Answer 23

Face, eyelid, genital, intertriginous

Question 24

Ointments are more or less potent than creams/lotions

Answer 24

MORE potent

allow better drug absorption

Question 25

How long to use Super high potent steroids

Answer 25

<4 weeks

Question 26

How long to use High and Medium potency steroids

Answer 26

<6-8 weeks

Question 27

How long to use Low potency steroids on face and other sensitive areas?

Answer 27

1-2 weeks

Question 28

Body Surface Area 1 Palm=

Answer 28

1% BSA

Question 29

Fingertip Unit. (FTU) on pad of finger from Tip to DIP joint

Answer 29

500 mg= treats 2% BSA

Question 30

Steroid cream; It takes 30 grams to cover an average adult body

Answer 30

for one application

Question 31

Common Topical Retinoids to treat Acne Vulgaris

Answer 31

Tretinoin Adapalene Tazarotene

Question 32

Topical Abx to tx Acne Vulgaris

Answer 32

Erythromycin 2% (solution, gel) Clindamycin 1% (lotion, solution, gel, foam)

Question 33

1st line tx for Mild Acne

Answer 33

Topical Retinoid OR Peroxide

Question 34

1st line tx for Moderate Acne

Answer 34

COMBO: Topical Retinoid, Peroxide +/- Topical Abx

Question 35

1st line tx for Severe Acne

Answer 35

COMBO: Topical Retinoid, Peroxide, Oral Abx +/- Topical Abx

Question 36

Nystatin

Answer 36

Better for candida, not dermatophytes

Question 37

Tinea Pedis tx

Answer 37

Terbinafine OR Miconazole (topical) BID 4-6 wks

Question 38

Tinea Corporis (body) tx

Answer 38

Terbinafine 2nd line: Miconazole BID daily until resolution, then continue for 2 more weeks

Question 39

1st line tx for Psoriasis

Answer 39

High potency topical steroid +/- topical vit D

Question 40

Super high potency steroid

Answer 40

Clobetasol prop

Question 41

High potency steroid

Answer 41

Fluocinonide cream | Mometasone ointment

Question 42

Medium potency steroid

Answer 42

Mometasone cream | Triamcinolone acetonide

Question 43

Low potency steroid

Answer 43

Fluocinolone ACETONIDE cream Desonide Hydrocortisone

Question 44

Desonide | Hydrocortisone

Answer 44

Low potency

Question 45

Clobetasol propionate

Answer 45

HIGH potency

Question 46

Triamcinolone acetonide

Answer 46

Medium potency

Question 47

Use on Scalp, palm, sole, and thick plaques on extensor surfaces

Answer 47

Clobetasol prop | HIGH potency

Question 48

Use on mild-mod NON facial and NON intertriginous Medium potency

Answer 48

Triamcinolone acetonide

Question 49

Use on Face, eyelid, genital, and intertriginous area

Answer 49

Desonide Hydrocortisone (LOW potency)

Question 50

AK | Actinic Keratoses

Answer 50

Dry, scaly Pre-CA Fair skinned pts Later in life (after 40s) after repeated sun exposure

Question 51

AK can progress to

Answer 51

Sq Cell CA

Question 52

Basal cell CA

Answer 52

most common type Pearly, flesh colored or pink, rolled borders

Question 53

Sq Cell CA

Answer 53

2nd most common type of skin CA

Question 54

Sq Cell CA

Answer 54

Red firm bump, scaly patch, or sore that Re-opens

Question 55

Melanoma

Answer 55

Can be deadly

Question 56

Melanoma

Answer 56

often develop in MOLE or new DARK SPOT

Question 57

Melanoma

Answer 57

``` A-asymmetry B-borders C-color D-diameter (>6 mm concerning, pencil eraser) E- evolving ```