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Clinical Prep > Dermatology > Flashcards

Dermatology Flashcards

1
Q

Most common form of skin CA

A

Basal cell CA-

Pearly, red papules or plaques with Rolled borders and Telangiectasias

sun exposed areas

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2
Q

Langerhans cells (can exit epidermis to travel to lymph nodes and present antigens) play a prominent role in

A

Allergic contact dermatitis, like

Poison ivy

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3
Q

Merkel cells

A

associated with touch, found more densely in touch-sensitive areas

discrimination of fine spatial details

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4
Q

Merkel cell Carcinoma

A

Rare, aggressive form of skin CA

Deep pink or Red nodule, may mimic a furuncle or inflamed cyst

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5
Q

Dermis includes:

A
  • Support
  • Collagen
  • Elastic fibers
  • Blood vessels
  • Lymph vessels
  • Nerves
  • Glands
  • Hair follicles
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6
Q

Apocrine glands found ONLY in

A

Axillary
Anogenital areas

These glands open DIRECTLY into hair follicle

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7
Q

Eccrine sweat glands

A

do NOT INVOLVE hair follicle.

Instead, open directly onto the skin

Present throughout body surface

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8
Q

Function of Eccrine sweat glands

all over body, open directly onto skin

A

Regulate body temp

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9
Q

Fibroblasts (resp for keloids, scarring) and Mast cells are found in the:

A

Dermis

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10
Q

Function of Subcutis

A

Fat layer that separates dermis from Underlying fascia and muscles

made of: Adipocytes and Connective tissue

Fx:
insulation, energy supply, cushion/protect skin, allow for skin’s mobility

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11
Q

If person is missing subcutis

A

Skin may be bound down, contractures to some limbs

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12
Q

Erythema Nodosum (a disorder of the Subcutis)

A

inflammation of subcutis. Appears as deep-seated red nodules, often on shins

Assoc w: GI infections, Sarcoidosis, Crohn’s dz

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13
Q

Epidermis (4 layers) from base up

A

Basal
Spinous
Granular
Corneum (top)

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14
Q

Common tx for Atopic Dermatitis and Psoriasis

A

Topical Steroid

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15
Q

Super high potency steroid

A

Class I

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16
Q

Steroids within any class are equal in strength

A

Strength is based on the molecule, not the concentration

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17
Q

Super high strength Steroid

A

Clobetasol propionate cream

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18
Q

Medium strength steroid

A

Mometasone

Triamcinolone

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19
Q

Low strength steroid

A

Desonide

Hydrocortisone

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20
Q

When deciding on the strength of a steroid, what is more important to look at?

A

CLASS

not the %
Class I is strongest, Class VII is weakest

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21
Q

Class I steroids are used for:

A

Scalp, palm, sole, thick plaque on extensor surface

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22
Q

Med-high potency, Class 2-5 steroids are used for

A

Mild-mod NONFACE and NONintergriginous areas

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23
Q

Low potency steroids (Class 6-7) are used for

A

Face, eyelid, genital, intertriginous

24
Q

Ointments are more or less potent than creams/lotions

A

MORE potent

allow better drug absorption

25
Q

How long to use Super high potent steroids

A

<4 weeks

26
Q

How long to use High and Medium potency steroids

A

<6-8 weeks

27
Q

How long to use Low potency steroids on face and other sensitive areas?

A

1-2 weeks

28
Q

Body Surface Area

1 Palm=

A

1% BSA

29
Q

Fingertip Unit. (FTU)

on pad of finger from Tip to DIP joint

A

500 mg= treats 2% BSA

30
Q

Steroid cream; It takes 30 grams to cover an average adult body

A

for one application

31
Q

Common Topical Retinoids to treat Acne Vulgaris

A

Tretinoin
Adapalene
Tazarotene

32
Q

Topical Abx to tx Acne Vulgaris

A

Erythromycin 2% (solution, gel)

Clindamycin 1% (lotion, solution, gel, foam)

33
Q

1st line tx for Mild Acne

A

Topical Retinoid
OR
Peroxide

34
Q

1st line tx for Moderate Acne

A

COMBO:
Topical Retinoid, Peroxide

+/- Topical Abx

35
Q

1st line tx for Severe Acne

A

COMBO:
Topical Retinoid,
Peroxide,
Oral Abx

+/- Topical Abx

36
Q

Nystatin

A

Better for candida, not dermatophytes

37
Q

Tinea Pedis tx

A

Terbinafine OR
Miconazole
(topical)

BID 4-6 wks

38
Q

Tinea Corporis (body) tx

A

Terbinafine

2nd line: Miconazole

BID daily until resolution, then continue for 2 more weeks

39
Q

1st line tx for Psoriasis

A

High potency topical steroid

+/- topical vit D

40
Q

Super high potency steroid

A

Clobetasol prop

41
Q

High potency steroid

A

Fluocinonide cream

Mometasone ointment

42
Q

Medium potency steroid

A

Mometasone cream

Triamcinolone acetonide

43
Q

Low potency steroid

A

Fluocinolone ACETONIDE cream
Desonide
Hydrocortisone

44
Q

Desonide

Hydrocortisone

A

Low potency

45
Q

Clobetasol propionate

A

HIGH potency

46
Q

Triamcinolone acetonide

A

Medium potency

47
Q

Use on Scalp, palm, sole, and thick plaques on extensor surfaces

A

Clobetasol prop

HIGH potency

48
Q

Use on mild-mod NON facial and NON intertriginous

Medium potency

A

Triamcinolone acetonide

49
Q

Use on Face, eyelid, genital, and intertriginous area

A

Desonide
Hydrocortisone

(LOW potency)

50
Q

AK

Actinic Keratoses

A

Dry, scaly
Pre-CA

Fair skinned pts
Later in life (after 40s) after repeated sun exposure

51
Q

AK can progress to

A

Sq Cell CA

52
Q

Basal cell CA

A

most common type

Pearly, flesh colored or pink, rolled borders

53
Q

Sq Cell CA

A

2nd most common type of skin CA

54
Q

Sq Cell CA

A

Red firm bump, scaly patch, or sore that Re-opens

55
Q

Melanoma

A

Can be deadly

56
Q

Melanoma

A

often develop in MOLE or new DARK SPOT

57
Q

Melanoma

A 
A-asymmetry
B-borders
C-color
D-diameter (>6 mm concerning, pencil eraser)
E- evolving

Clinical Prep (41 decks)

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