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PANCE > Dermatology 5% > Flashcards

Dermatology 5% Flashcards

1
Q

Vesicular lesions on palms that break and then crack. Tapioca Pudding appearance

A

Dishydrotic eczema. Tx: corticosteroids

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2
Q

Pruritic, sharply demarcated, coin shaped lesions on back of hands, feet, and extensor surfaces

A

Nummular eczema

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3
Q

Lichen Planus is associated with what condition?

Clinical manifestation:

A

Hepatitis C

5 Ps: purple, polygonal, planar, pruritic, papules w/ fine scales

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4
Q

What conditions are associated with erythema nodosum?

A

Pregnancy, sarcoidosis, TB

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5
Q

Can mimic syphilis so do PRP if pt is sexually active with this skin manifestation.

A

Pityriasis Rosea

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6
Q

Keratin hyperplasia (proliferating cells in stratus basale + stratum spinosum) d/t ______ =

A

T-cell activation and cytokine release

Psoriasis

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7
Q

Auspitz sign =

Seen in ___

A

Punctuate bleeding w/ removal of plaque

Psoriasis, actinic keratosis

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8
Q

Pityriasis versicolor caused by ___

Dx w/:

Tx:

A

Malassezia furfur

KOH prep: hyphae + spores “spaghetti and meatball” appearance
Wood’s lamp: yellow-green fluorescence

Tx: Selenium sulfide*
Sodium sulfacetamide
Azole antifungals

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9
Q

Type I Hypersensitivity Reaction

A

IgE mediated

Ex: Urticaria, angioedema

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10
Q

Type II Hypersensitivity Reaction

A

Cytotoxic, Ab-mediated

Ex: drugs + cytotoxic abs –> cell lysis

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11
Q

Type III Hypersensitivity Reaction

A

Immune antibody-antigen complex

Ex: drug-mediated vasculitis, serum sickness

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12
Q

Type IV Hypersensitivity Reaction

A

Delayed (cell mediated)

Ex: Erythema Multiforme

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13
Q 
MC causes of Exanthematous/Mobiliform Rash include all of the following EXCEPT:
A. Abx
B. NSAIDs
C. Colchicine 
D. K+ sparing diuretics
A

C, D
Allopurinol
Thiazide diuretics

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14
Q 
MC causes of Erythema Multiforme include all of the following EXCEPT:
A. Sulfonamides
B. Macrolides
C. Phenobarbital
D. Dilantin
A

B. Penicillins

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15
Q

What’s the difference between Erythema multiforme MAJOR and MINOR?

A

Minor: No mucosal membrane lesions

Major: >1 mucous membrane involvement
No epidermal detachment

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16
Q

Erythema multiforme = Type ___ Hypersensitivity

A

4

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17
Q

Urticaria/angioedema = Type ___ Hypersensitivity

A

1

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18
Q

Sloughing > ___% = Toxic Epidermal Necrolysis

A

30%

<10% = Steven-Johnson Syndrome

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19
Q

4 main pathophysiologic factors in Acne Vulgaris

A
  1. increased sebum production ( increased androgen in puberty)
  2. Blogged sebaceous glands
  3. Proprionibacterium acne overgrowth
  4. Inflammatory response
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20
Q

SE of Isotretinoin

A
  • Highly teratogenic: 2 pregnancy tests before starting + monthly while on it
  • Hepatitis
  • Increased triglycerids/cholesterol

Tx of severe Acne Vulgaris

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21
Q

1st line treatment of Rosacea =

___ may be used for flushing.

A

Topical metronidazole

Clonidine

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22
Q

PainLESS, soft, fleshy, cauliflower like lesion in genital region =

Caused by ___

A

Condyloma acuminata

HPV

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23
Q

Dx of mucosal HPV infection (warts)

A

whitening of lesion w/ acetic acid application

24
Q

Painful, erythematous inflammatory nodules seen on anterior shins =

Etiologies include (4)

A

Erythema Nodosum

  • Estrogen exposure (OCP, pregnancy)
  • Sarcoidosis
  • Infection: strep, TB, sarcoid, fungal (Coccidioidomycosis*)
  • Inflammatory d/o: IBD, leukemia, Behcet disease
25
Q

Kaposi Sarcoma = connective tissue cancer caused by ___.

Seen in ___.

Tx:

A

HHV-8

HIV/immunosuppressive patients

HAART therapy

26
Q

Tx of Impetigo

A

Mupirocin (bactroban)** TID x 10 days

Systemic abx:
Cephalexin
Dicloxacillin
Erythromycin/azithromycin
Clindamycin
27
Q

Tx of cellulitis

A

Cephalexin, Dicloxacillin x 7-10 days

PCN allergies: Erythromycin, Clindamycin

28
Q

Cat bite pathogen =

Tx:

A

Pasteurella multocida
Tx: Augmentin
PCN allergy: Doxycycline

29
Q

Puncture wound through shoe should have tx that covers for ____. Tx =

A

Pseudomonas

Ciprofloxacin

30
Q

Paronychia =

A

infection of nail margin

31
Q

Tx of choice for pediculosis

A

(lice)

Permethrin topical

32
Q

Red itchy pruritic papules or nodules on scrotum, glans, or penile shaft, body folds =

A

scabies

33
Q

Tx of choice for scabies

A

Permethrin topical

34
Q

Lindane

A

Cheaper tx for scabies
Do NOT use p bath/shower –> may cause seizures d/t increased absorption through open pores
CI: Teratogenic, do not use in breastfeeding women, < 2 y/o

35
Q

Autoimmune d/t secondary to desmosome disruption =

Type ___ Hypersensitivity.

(+/-) Nikolsky sign

Biopsy shows ___.

Tx:

A

Pemphigus vulgaris

Type II HSN

POSITIVE Nikolsky sign

IgG throughout epidermis

Tx: Systemic corticosteroids

36
Q

Autoimmune attack on basement membrane causing SUBEPIDERMAL blistering =

Type ___ Hypersensitivity.

(+/-) Nikolsky sign

Tx:

A

Bullous pemphigoid
(elderly)

Type II HSN

NEGATIVE Nikolsky sign

Tx: corticosteroids

37
Q

Tx of brown recluse spider bite

A

Dapsone

38
Q

What degree of burn?

  • Red, yellow, pale, white
  • Dry
    • blistering
  • not painful
  • ABSENT capillary refill
A

2nd degree: Deep partial thickness

39
Q

What degree of burn?

  • Moist, weeping
  • +blistering
  • MOST PAINFUL
  • PRESENT capillary refill
A

2nd degree: superficial partial thickness

40
Q

Parkland Formula =

Used for ____.

A

= 4 x mass (kg) x area of burn (% TSA)
Give 1/2 in 1st 8 hrs
Rest in last 16 hrs

Used in burn IV fluid resuscitation

41
Q

Rule of 9s

A 
9% head
9% each arm
18% each leg
18% anterior torso (chest + abdomen)
18% posterior torso
1% perineum
1% hand
42
Q

Silvadene used for ____.

CI:

A

Burn management: abx

CI: sulfa allergies, pregnancy, < 2 months
Do NOT use on face d/t discoloration

43
Q

Keloid = excess production of ____ during wound healing.

A

Type III collagen

44
Q

Coxackie A causes

A
  • Hand, foot, mouth disease

- Herpangina –> sudden onset of high fever, Stomatitis

45
Q

Coxackie B causes

A

Pericarditis (MC cause)
Myocarditis (MC cause)
Pleurodynia = severe pleuritic chest pain w/ swelling over diaphragm, HA

46
Q

Dermatitis Herpetiformis is strongly associated w/ ___.

_____ deposition in ____.

Tx:

A

Celiac disease

IgA immune complex deposition in dermal papillae

Tx: Gluten free diet, Dapsone*

47
Q

MC cause of acute pancreatitis in children

A

Mumps

48
Q

Mumps caused by ____ pathogen.

A

Paramyxovirus

49
Q

MMR vaccine given ____

A

12-15 months

4-6 y/o

50
Q

Paramyxovirus causes

A

Mumps

Rubeola (Measles)

51
Q

Solitary glistening friable red nodule or papule that may bleed or ulcerate MC in children/young adults after trauma.

Tx:

A

Pyogenic granuloma (misnomer)

Topical Imiqod, alitretinoin gel

52
Q

Pyoderma gangrenosum associated w/ ____.

Tx:

A

Inflammatory disease: RA, IBD, spondyloarthropathies , etc.

Topical steroids
Tacrolimus

53
Q

ulcerative skin lesion 2ndary to immune dysregulation +/- preceded by trauma

A

Pyoderma gangrenosum

54
Q

“3 day rash” caused by Togavirus

A

Rubella (German Measles)

55
Q

Recurrent erythema multiforme is MC d/t ____.

A

recurrent herpes simplex virus outbreak

56
Q

1st line treatment of hidradenitis suppurativa

A

Intralesional triamcinolone

57
Q

Trichophyton rubrum is the most common cause of ___

A

athlete’s foot

PANCE (20 decks)

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