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Techno II > Dermatika > Flashcards

Dermatika Flashcards

1
Q

TTS was ist nicht sinnvoll?

A

WSt. mit langer HWZ, mit hoher Dosierung, große/hydrophile WSt.

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2
Q

Kontrollmechnismen TTS?

A

Matrix, Membran, Mirkoreservoir

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3
Q

Versorgung der Hornhaut?

A

Über Diffusion durch darunterliegende Dermis

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4
Q

Klebstoffmasse Sprühplaster?

A

Fumarsäureester-Copolymerisate

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5
Q

Auf was testet man mit zylindrischen Teil?

A

Wirkstofffreisetzung (rotierender Zylinder)

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6
Q

2 Öle für WSt-Reservoir?

A

Geliertes Mineralöl, Silikonöl

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7
Q

An welcher Stelle beste Resorption?

A

Scrotum, Hinterohrregion, Stirn

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8
Q

Membrankontrollierte Systeme?

A

Polyethylen, Polypropylen, Polyisobutlyen, Silikon

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9
Q

Geringste Tiefenwirkung auf die Haut?

A

Puder, Schüttelmixturen

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10
Q

WSt. für Iontophorese?

A

anionisch und kationische geladene, z.B. Insulin

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11
Q

Größte Tiefenwirkung auf die Haut?

A

Pflaster und Umschläge

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12
Q

Klebstoffe?

A

Naturkautschuk, Silikone, Polyacrylate (Ethyl-, Butyl-, Ethylhexylpolyacrylsäure), Polyisobutylen, Fumarsäureester-Copolymerisate

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13
Q

WSt. in TTS?

A

Hochwirksame, lipophile, geringe Molekülmasse (< 500 Da) —> hoher Permeationskoeffizient, geringe HWZ, geringer dermaler FPE —> Bsp. Hormone, Nikotin, Nitroglycerin, Scopolamin, Fentanyl

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14
Q

Chemische Verbindungen im Naturkautschuk?

A

Cis-1,4-Polyisopren

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Techno II (11 decks)

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