Derma 3 Flashcards
Irreversible Inhibitor of protein syn; binds to 30s; Active against gram (-)
Aminoglycosides
- Neomycin
- Gentamicin
Interferes with cell wall formation by dephosphorylation
Bacitracin
Adverse event of Aminoglycosides
Allergic contact dermatitis
Adverse event of Bacitracin
Urticaria and Allergic contact dermatitis
Inhibits staph isoleucyl tRNA synthase; For Gram (+)
Mupirocin
Adverse effect of Mupirocin
Irritation of Mucous membrane
Cationic detergent which attach and disrupt bacterial cell membrane; bind and inactivates endotoxin For Gram (-)
Polymixin B sulfate
Adverse event of Polymixin
Nephrotoxicity
Neurotoxicity
Against Grp A B-hemolytic strep and S. Aureus
Retapamulin
Name the Antibacterial Drugs
Bacitracin Polymixin B sulfate Aminogylcoside Retapamulin Mupirocin (BP ARM)
Target Gram (-)
Aminoglycoside
Polymixin B sulfate
Inhibits Fungal squalene epoxidase
Allylamines
- Naftifine
- Terbinafine
Adverse effect of Allylamine
Local irritation
Burning sensation
Erythema
Reduction of Ergol Syn by inhibition of fungal CYP450
Azole
Active against dermatophyte
Tolnaftate
Treatment for head lice
Benzyl Alcohol
Name the antifungal drugs
Allylamines
Azole
Tolnaftate
Treatment for Scabies
Crotamiton
Treatment for Pediculosis capitis and pubis; also for Scabies
Lindane
Permethrin
Absorbed in fatty tissues including the brain
Lindane
Lipid
An organophosphate cholinesterase inhibitor; against pediculosis
Malathion
Name the topical ectoparasite drugs
Benzyl Alcohol Crotamiton Lindane Malathion Permethrin Sulfur (BCLaMPS)
