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Pharmacology > Derma 3 > Flashcards

Derma 3 Flashcards

1
Q

Irreversible Inhibitor of protein syn; binds to 30s; Active against gram (-)

A

Aminoglycosides

  • Neomycin
  • Gentamicin
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2
Q

Interferes with cell wall formation by dephosphorylation

A

Bacitracin

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3
Q

Adverse event of Aminoglycosides

A

Allergic contact dermatitis

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4
Q

Adverse event of Bacitracin

A

Urticaria and Allergic contact dermatitis

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5
Q

Inhibits staph isoleucyl tRNA synthase; For Gram (+)

A

Mupirocin

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6
Q

Adverse effect of Mupirocin

A

Irritation of Mucous membrane

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7
Q 
Cationic detergent which attach and disrupt bacterial cell membrane; bind and inactivates endotoxin
For Gram (-)
A

Polymixin B sulfate

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8
Q

Adverse event of Polymixin

A

Nephrotoxicity

Neurotoxicity

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9
Q

Against Grp A B-hemolytic strep and S. Aureus

A

Retapamulin

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10
Q

Name the Antibacterial Drugs

A 
Bacitracin
Polymixin B sulfate
Aminogylcoside
Retapamulin
Mupirocin
(BP ARM)
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11
Q

Target Gram (-)

A

Aminoglycoside

Polymixin B sulfate

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12
Q

Inhibits Fungal squalene epoxidase

A

Allylamines

  • Naftifine
  • Terbinafine
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13
Q

Adverse effect of Allylamine

A

Local irritation
Burning sensation
Erythema

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14
Q

Reduction of Ergol Syn by inhibition of fungal CYP450

A

Azole

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15
Q

Active against dermatophyte

A

Tolnaftate

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16
Q

Treatment for head lice

A

Benzyl Alcohol

17
Q

Name the antifungal drugs

A

Allylamines
Azole
Tolnaftate

18
Q

Treatment for Scabies

A

Crotamiton

19
Q

Treatment for Pediculosis capitis and pubis; also for Scabies

A

Lindane

Permethrin

20
Q

Absorbed in fatty tissues including the brain

A

Lindane

Lipid

21
Q

An organophosphate cholinesterase inhibitor; against pediculosis

A

Malathion

22
Q

Name the topical ectoparasite drugs

A 
Benzyl Alcohol
Crotamiton
Lindane
Malathion
Permethrin
Sulfur
(BCLaMPS)

Pharmacology (8 decks)

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