Derm Pharm Flashcards
1
Q
Rate limiting step of cutaneous absorption
A
Transgressing the stratum corneum
2
Q
Partition coefficient
A
Ability of the drug to leave the vehicle.
3
Q
What determines the effectiveness of a topical medication?
A
The clinical outcome. The exact amount of drug entering or leaving the skin in clinical situations is usually not measured.
4
Q
In what ways does propylene glycol improve absorption of topical medication?
A
Improves hydration of stratum corneum. Also enhances desquamination
5
Q
Hypersensitivity Rxn from topical medications
A
Any topical can cause. Rare reports with OTC acne medications (Benzoyl peroxide, salicylic acid)
6
Q
A
