Derm emergencies Flashcards
What is eczema herpeticum?
Complication of atopic eczema due to herpes simplex virus
What is the presentation of eczema herpeticum?
- Extensive blisters and erosion
* Systemically unwell =fever and malaise
What is the treatment of eczema herpeticum?
- Admit
- Viral and bacterial swabs
- IV aciclovir 48hrs
- Treat 2ndary bacterial infection
What is morbilliform?
- A skin reaction due to drugs
* Typer IV hypersensitivity reaction
What is the presentation of morbilliform?
- 5-10days onset
- Fever/malaise
- maculopapular, symmetrical
- Can progress to erythroderma/TEN
What is the management of morbilliform?
- Stop likely offending drug
- Bloods
- Supportive treatment: antihistamine, emollients/soap, topical steroid
What is DRESS reaction?
- Drug Reaction with Eosinophilia and Systemic Symptoms
- skin reaction
- Type 4 hypersensitivity reaction
What is the presentation of DRESS?
- Widespread rash
- Pustules
- Erythroderma
- multi organ involvement: hepatitis, pericarditis, lymphadenopathy, pneumonitis, interstitial nephritis
What is the diagnostic criteria for DRESS?
- Hospitalisation
- Suspected drug reaction
- Acute skin rash
- Fever >38
- Lymphadenopathy at 2 sites
- At least 1 organ involved
- thrombocytopenia/eosinophilia
What is the management of DRESS?
*Admit
*Stop offending drug
*Supportive treatment:
>Antihistamine
>emollients
>topical steroids
*Refere to derm
What is erythroderma?
*Intense, widespread reddening of skin due to inflammatory skin disease
“red man syndrome”
What is the presentation of erythroderma?
- Acute/chronic
- Widespread redness
- exfoliation of skin surface
- Pruritis
- hair loss
- hyperkeratosis palms
- lymphadenopathy
What is the management of erythroderma?
- Admit
- skin swab and bloods
- Bland emollients
- Thermoregulation
- Fluid balance
- Antibiotics
- Antihistamines
What is the presentation of steven johnsons syndrome/toxic epidermal necrolysis (TEN)?
*Widespread blisters, predominant on trunk & face
*Erythematous or pruritic macules
*Targetoid lesions
*Mucous membrane involvement
*Epidermal detachment:
<10% SJS
>30% in TEN
What is the cause of stevens johnson syndrome/TEN?
- Drugs
* HLA genetic association