Derm emergencies Flashcards

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1
Q

what is overlap of steven johnson and toxic epidermal necrolysis

A

SJS - 10% body area

TEN - 30%

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2
Q

morpho of SJS

A
  • dusky tender skin
  • mucous membrane involved
  • bullae
  • skin sloughing
  • atypical targets
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3
Q

cause of SJS

A

DRUGS

  • Abx
  • anticonvusants
  • NSAIDs
  • allopurinol
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4
Q

mgmt of SJS

A
  1. diagnose early
  2. STOP DRUG
  3. supprtive care - burn unit
  4. immunosppuress
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5
Q

what is henoch sheinlen pupura

A
  • inflammation and nercrosis of blood vessels
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6
Q

skin manifestations of HSP

A
  • palpable purpura
  • vesicles
  • livedo - laceliek stuff
  • ulcers and nodules
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7
Q

causes of vascultis

A
  • just about anything
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8
Q

how is vasculitis classified

A

by size of vessel

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9
Q

how to treat vasculitis

A

depends on where
systemic workup
skin - nothing
other - steroids, cyclophosphamide

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10
Q

what is pemphigus vulgaris

A
  • starts with oral sores

- moves on to progression of flaccid blisters all over

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11
Q

cause of pemphigus vulgaris

A

autoimune

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12
Q

Tx of pemphigus vulgaris

A
  • high dose immunosupressants
  • prednisone
  • other steroid sparing agents
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13
Q

what is bullous pemphigoid

A
  • tense blisters of urticarial skin
  • pruritis
  • usually elderly
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14
Q

cause of bullous pemphigoid

A
  • drugs

- autoimune

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15
Q

mgmt of bullous pemphigoid

A
  • prednisone

- if mild can try topical clobetasol

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16
Q

what is nec fascitis

A
  • infection of sub-cut fat and fascia
  • ## rapidly progressive necrosis
17
Q

signs and Sx of nec fasc

A
  • exquisite tenderness
  • erythema evolving to dusky grey
  • woody erethyma
  • maloderous discharge
18
Q

Tx of nec fasc

A
  • stabilize and admit
  • broad spectrum ABx
  • surgical debridment
19
Q

what is drug hypersensitivity syndrome

A
  • 2-6 weeks after the drug
  • fever/malaise
  • mobiliform rash
  • facial edema
  • lymphadenopathy
20
Q

Tx of drug hypersens

A
  • stop the drug
  • ## supportive care