Derm

Question 1

Hydroxyzine, Diphenhydraine, Doxepine

MOA?

Answer 1

Anti-histamine for severe atopic dermatitis

Question 2

Tacrolimus, pimecrolimus Use and severe SE?

Answer 2

Taper off steroids for atopic dermatitis, sensitive areas of psoriasis

Low risk of lymphoma

Question 3

Etanercept, adalimumab, inflixumab MOA

use?
S/e?

Answer 3

Anti-TNFa

Severe Psoriasis
Reactivates Tb (do ppd before starting)

Question 4

Pemphigus Vulgaris vs. Bullous pemphigoid
Causes
Signs
Tx?

Answer 4

PV (Desmosome ab)

• ACEI, penicillamine, penicillin
• Nickolsky +, thin walled
• Steroids, mycophenolate, rituxumab

BP (hemi-desmosome ab)

• Furosemide, NSAIDs
• Nickolsky -, don’t rupture
• Dapsone, nicotinamide, Steroids, mycophenolatelister

Question 5

Blistering skin in sun exposed areas?

Cause?

Answer 5

PCT

HepC
Estrogen
Fe Overload

Question 6

Erysipelas vs. Impetigo?

Answer 6

E

• Strep > staph
• Leukocytosis, deeper infx
• Still cover for staph

I

• Staph > Strep
• Milder, weeping blistering
• Mupirocin, clinda, Bactrim

Question 7

Staph + gram(-) coverage?

Answer 7

Augmentin
Zosyn
Amp/sulbat
Ticaracillin/clav

2nd gen cephalosporing

Question 8

SJS and TEN tx?

Answer 8

SJS = 30% body

IVIG
steroids unclear in SJS, not effective in TEN

Question 9

TEN vs. SSSS?

Answer 9

Both +nickolsky and mucous membrane involvement

SSSS has other organs
Low BP, Renal failure, Liver dysfunction, AMS

Question 10

1-3 day old Infant with red papules, pustules, vesivles?

Answer 10

Erythema toxicum neonatorum

Question 11

Infant scaly rash on head?

Answer 11

Cradle cap = seborrheic dermatitis
(Malassezia furfur hypersensitivity)

tx: emollient application, wait

Question 12

adult seborrheic dermatitis tx?

Answer 12

Selenium sulfide

Question 13

Infant with grouped vesicles on face with hx of eczema?

Answer 13

eczema herpeticum (HSV)

TX: IV acyclovir

Question 14

Sausage digits and “pencil in cup” on hand Xray?

Answer 14

Psoriatic arthritis

Question 15

Anterior shin painful erythematous nodules?

Causes?

Answer 15

Erythema Nodosum

• Coccidiodes
• Yersinia
• Tb (ppd)
• Streptococcus (ASO titer)
• Chron’s/UC (Colonoscopy)
• Sarcoid (CXR)

Question 16

Dermaitits herpetiformis tx?

Answer 16

Dapsone

Question 17

Nec fasc tx?

Answer 17

1) Penicillin G (strep)
2) clinda (staph)
3) metronidazole (Anaerobic)

Question 18

Labs to check before starting Isoretinon for acne?

Answer 18

LFT
Cholesterol
Triglyceride
PREGNANCY

Question 19

Small pink papules on truck + GI symptoms?

tx?

Answer 19

Salmonella typi

Flouroquinolones + cefox/fur/fotax

Question 20

Rosacea tx?

Answer 20

Topical metronidazole

Question 21

Cherry vs. Strawberry hemangioma?

Answer 21

Cherry = Adult

Strawberry = Child, grows before it sontaneously resolves

Question 22

SCC vs BCC timeline, common?

Answer 22

BCC = slower, more COMMON

Question 23

Acne treatment 1-3?

Answer 23

1 - topical benzoyl/tretinoin

2 - Topical ABX

3- Oral ABX, oral isotretinoin

Question 24

Large, progressive ulcer of lower extremity with purulent base and violaceous borders?
Association?
Dx?
Tx?

Answer 24

Pyoderma gangrenosum

IBD, RA, SLE, AML

Biopsy

Steroids

Question 25

SLE ab tests order? Sens and spec?

Answer 25

ANA = High sens (1st)

Anti-smith/dsDNA = High spec (2nd)