Derm Flashcards
Hydroxyzine, Diphenhydraine, Doxepine
MOA?
Anti-histamine for severe atopic dermatitis
Tacrolimus, pimecrolimus Use and severe SE?
Taper off steroids for atopic dermatitis, sensitive areas of psoriasis
Low risk of lymphoma
Etanercept, adalimumab, inflixumab MOA
use?
S/e?
Anti-TNFa
Severe Psoriasis Reactivates Tb (do ppd before starting)
Pemphigus Vulgaris vs. Bullous pemphigoid
Causes
Signs
Tx?
PV (Desmosome ab)
- ACEI, penicillamine, penicillin
- Nickolsky +, thin walled
- Steroids, mycophenolate, rituxumab
BP (hemi-desmosome ab)
- Furosemide, NSAIDs
- Nickolsky -, don’t rupture
- Dapsone, nicotinamide, Steroids, mycophenolatelister
Blistering skin in sun exposed areas?
Cause?
PCT
HepC
Estrogen
Fe Overload
Erysipelas vs. Impetigo?
E
- Strep > staph
- Leukocytosis, deeper infx
- Still cover for staph
I
- Staph > Strep
- Milder, weeping blistering
- Mupirocin, clinda, Bactrim
Staph + gram(-) coverage?
Augmentin
Zosyn
Amp/sulbat
Ticaracillin/clav
2nd gen cephalosporing
SJS and TEN tx?
SJS = 30% body
IVIG
steroids unclear in SJS, not effective in TEN
TEN vs. SSSS?
Both +nickolsky and mucous membrane involvement
SSSS has other organs
Low BP, Renal failure, Liver dysfunction, AMS
1-3 day old Infant with red papules, pustules, vesivles?
Erythema toxicum neonatorum
Infant scaly rash on head?
Cradle cap = seborrheic dermatitis
(Malassezia furfur hypersensitivity)
tx: emollient application, wait
adult seborrheic dermatitis tx?
Selenium sulfide
Infant with grouped vesicles on face with hx of eczema?
eczema herpeticum (HSV)
TX: IV acyclovir
Sausage digits and “pencil in cup” on hand Xray?
Psoriatic arthritis
Anterior shin painful erythematous nodules?
Causes?
Erythema Nodosum
- Coccidiodes
- Yersinia
- Tb (ppd)
- Streptococcus (ASO titer)
- Chron’s/UC (Colonoscopy)
- Sarcoid (CXR)
Dermaitits herpetiformis tx?
Dapsone
Nec fasc tx?
1) Penicillin G (strep)
2) clinda (staph)
3) metronidazole (Anaerobic)
Labs to check before starting Isoretinon for acne?
LFT
Cholesterol
Triglyceride
PREGNANCY
Small pink papules on truck + GI symptoms?
tx?
Salmonella typi
Flouroquinolones + cefox/fur/fotax
Rosacea tx?
Topical metronidazole
Cherry vs. Strawberry hemangioma?
Cherry = Adult
Strawberry = Child, grows before it sontaneously resolves
SCC vs BCC timeline, common?
BCC = slower, more COMMON
Acne treatment 1-3?
1 - topical benzoyl/tretinoin
2 - Topical ABX
3- Oral ABX, oral isotretinoin
Large, progressive ulcer of lower extremity with purulent base and violaceous borders?
Association?
Dx?
Tx?
Pyoderma gangrenosum
IBD, RA, SLE, AML
Biopsy
Steroids
SLE ab tests order? Sens and spec?
ANA = High sens (1st)
Anti-smith/dsDNA = High spec (2nd)