Derm Flashcards

1
Q

Vitiligo- associated conditions?

A

type 1 diabetes mellitus
Addison’s disease
autoimmune thyroid disorders
pernicious anaemia
alopecia areata

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2
Q

Scarring vs non-scarring alopecia?

A
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3
Q

itchy papular rash on her palms, extending onto the flexor aspect of the forearms.
White lines are visible across the surface of the rash.

what is it? tx?

A

lichen planus
purple, pruritic, papular, polygonal rash on flexor surfaces. Wickham’s striae over surface.

potent topical steroids are the mainstay of treatment

think !!! -lichen sclerosus: itchy white spots typically seen on the vulva of elderly women

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4
Q

hair loss following stressful period e.g. surgery?

A

Telogen effluvium is the loss and thinning of hair in response to severe stress

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5
Q

severe acne: predominantly papular/pustular with nodules and scarring.
tx?

A

oral abx (tetracycline, oxytetracycline, doxycycline, or lymecycline ) and topical benzoyl peroxide

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6
Q
A

Hereditary haemorrhagic telangiectasia

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7
Q

describes features of Basal cell carcinoma?

A

rolled, pearly edges with telangiectasia on the inferior border of the lesion

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8
Q

Psoriasis: management

A

Topical steroid + topical calcipotriol

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9
Q

Rosacea (sometimes referred to as acne rosacea) presentation and tx (mild vs moderate)?

A
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10
Q

Erythema nodosum causes:
infection?
systemic?
drugs?

A

think CARBAMAZEPINE

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11
Q

Drugs cause this?

A

erythema multiforme

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12
Q

Squamous cell carcinoma most common risk factors?

A
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13
Q

Dermatitis herpetiformis

explain rash?
pathophysiological process

A

formation of IgA antibodies

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14
Q

Zinc deficiency features?

A
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15
Q

name a rash that develop acutely over several days 1-2 weeks after a streptococcal infection

(this patient has just had bacterial tonsillitis, which is typically caused by group A streptococcus infection).

A

GUTTATE PSORIASIS

Teardrop

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16
Q

Keratoacanthoma dx via GP

mx

A

urgent derm referral

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17
Q

narrowband ultraviolet B light and psoralen + ultraviolet A light (PUVA) used in secondary care mx for psoriasis- ADVERSE EFFECT?

A
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18
Q

3-year-old son who suffers from eczema
eczema has become a lot worse this week
He has developed widespread itchy blisters all over his body: including his face, torso, arms and legs.

dx? tx?

A

Eczema herpeticum is a serious condition that requires IV antivirals

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19
Q

26-year-old woman presents with a recurrent, intensely itchy rash on the palms of her hands.

they tend to occur every summer.

A

Pompholyx eczema may be precipitated by humidity (e.g. sweating) and high temperatures

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20
Q

three-week history of an itchy rash over the face and upper chest

PMx: HIV for which he is poorly compliant

rash? tx

A

Seborrhoeic dermatitis - first-line treatment is topical ketoconazole

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21
Q
A
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22
Q
A
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23
Q

stress ulcer that can occur after severe burns?

stress ulcer that occurs in the aftermath of severe head trauma.

A

Curling’s ulcer is a stress ulcer that can occur after severe burns

Cushing’s ulcer is a stress ulcer that occurs in the aftermath of severe head trauma.

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24
Q

rash in pregnancy?

A
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25
Q
A
26
Q

50 yo
symmetrical erythematous lesions are found with an orange peel texture.

A

Grave’s disease, orange peel shin lesions - pretibial myxoedema

27
Q

A 23-year-old female presents with red, thickened skin on the soles. On closer inspection a crop of raised lesions are seen.

A

Palmoplantar pustulosis

28
Q

22-year-old man presents with a 3 cm area of hyperkeratotic skin on the heel of his right foot. A number of pinpoint petechiae are seen in the lesion.

A

Mosaic wart

29
Q

excessively smelly feet. On examination he has white skin over the sole of the forefoot bilaterally. Small holes can be seen on the surface of the affected skin.

A

Pitted keratolysis

30
Q

Acute onset of tear-drop scaly papules on trunk and limbs

A

guttate psoriasis

31
Q

Itchy

A

single well-demarcated, erythematous circular patch with a raised edge and central hypopigmentation. Combined with the history of itch, the most likely diagnosis is tinea corporis (ringworm).

causes include Trichophyton rubrum and Trichophyton verrucosum (e.g. From contact with cattle)

32
Q

bullous pemphigoid vs pemphigus vulgaris

A

pemphigus vulgaris: blisters are flaccid and easily ruptured when touched.

33
Q

15-year-old female presents to ambulatory care with a painful pruritic rash that has rapidly worsened over the last 10 hours.

On examination, she has a monomorphic rash with punched out erosions over her cheeks and bilateral dorsal wrists. She is admitted for IV antivirals and observation.

?

A

Eczema herpeticum is a primary infection of the skin caused by herpes simplex virus (HSV)

34
Q

itchy white spots typically seen on the vulva of elderly women

A

Lichen sclerosus

35
Q

allergic contact dermatitis
dx?

A

skin patch test

36
Q

mild acne, open and closed comedones (blackheads and whiteheads)

tx?

A

Prescribe a topical retinoid (tretinoin, isotretinoin, or adapalene) or benzoyl peroxide (especially if papules and pustules are present) as first-line treatment.

azelaic acid if both topical retinoids and benzoyl peroxide are poorly tolerated.

37
Q

common complications of seborrhoeic dermatitis

A

Otitis externa and blepharitis

38
Q

78 year-old woman presents with a poorly healing area of skin on her ankle.

shallow ulcer anterior to the medial malleolus.

dx?
tx?

A

Venous ulceration

39
Q

Keloid scars tx?

A

early keloids may be treated with intra-lesional steroids e.g. triamcinolone

40
Q

……..are a vascular birthmark that do not spontaneoulsy resolve

A

port of wine stain

41
Q

Scalp psoriasis - first-line treatment?

A

topical potent corticosteroids

42
Q

Molluscum contagiosum

cause? tx?

A

virus (MCV), a member of the Poxviridae family.

Reassure people that molluscum contagiosum is a self-limiting condition.
Spontaneous resolution usually occurs within 18 months

43
Q

benign, painful nodule on the ear, more common in men than women?

A

Chondrodermatitis nodularis

44
Q

bilateral erythematous lesions on her shins surrounded by telangiectasia

A

Necrobiosis lipoidica

45
Q
A

Pyogenic granuloma is a relatively common benign skin lesion.

46
Q

factors may exacerbate psoriasis:

A

trauma
alcohol
drugs: beta blockers, lithium, antimalarials (chloroquine and hydroxychloroquine),

NSAIDs and ACE inhibitors,
infliximab
withdrawal of systemic steroids

47
Q

classic descriptions for polycythemia?

A
48
Q

Nail changes that may be seen in psoriasis

A

pitting
onycholysis (separation of the nail from the nail bed)
subungual hyperkeratosis
loss of the nail

49
Q

first-line for hyperhidrosis

A

Topical aluminium chloride

50
Q

serious cutaneous form of T-cell lymphoma that can present like eczema or psoriasis

A

Mycosis fungoides

51
Q

Acne vulgaris in pregnancy- oral abx choice?

A

oral erythromycin

52
Q

sebaceous cyst mx?

A

Surgical excision of sebaceous cyst as a whole structure is required to prevent reoccurrence

53
Q

Scabies is caused by

mx?

A

mite Sarcoptes scabiei

54
Q

Toxic epidermal necrolysis (TEN presentation?

what causes it?

A

potentially life-threatening skin disorder that is most commonly seen secondary to a drug reaction.

positive Nikolsky’s sign: the epidermis separates with mild lateral pressure

55
Q

Bullous pemphigoid skin biopsy?

A

immunofluorescence shows IgG and C3 at the dermoepidermal junction

56
Q

Impetigo mx?

A

topical fusidic acid if hydrogen peroxide not suitable

extensive: oral flucloxacillin
oral erythromycin if penicillin-allergic

57
Q
A

actinic keratosis

58
Q

dimples when pressure is applied.

A

dermatofibromas,

59
Q

Pemphigoid gestationis vs Polymorphic eruption of pregnancy

A

Pemphigoid gestationis: BLISTERS - 2ND, 3RD TRIMESTER

Polymorphic eruption of pregnancy is not associated with blistering- 3RD TRIMESTER

60
Q

Dermatophyte nail infections MX>

A

oral terbinafine

61
Q

Acne vulgaris: management

Should be avoided due to an increased risk of drug-induced lupus and hyperpigmentation?

A

Oral minocycline

62
Q

Acne vulgaris: management

most likely to affect the hepatic metabolism of other medications

A

Oral erythromycin