Depression Flashcards
Affective disorders
Set of psychiatric disorders, also called mood disorders.
Main types of affective disorders
Depression
Bipolar disorders
Major depression
Major depressive disorder (MDD), is a mental disorder characterised by at least two weeks of low mood that is present across most situations. It is often accompanied by low self-esteem, loss of interest in normally enjoyable activities, low energy, and pain without a clear cause.
Monoamine hypothesis of affective disorders
Predicts that the underlying pathophysiologic basis of depression involves deficits of in the levels of serotonin, noradrenaline and/or dopamine in the central nervous system
Diathesis-stress hypothesis of affective disorders
Suggests that exaggerated or hypersensitivity of the hypothalamic-pituitary-adrenal axis is at the centre of the neurobiology of this disorder
Electroconvulsive therapy (ECT)
Procedure, done under general anaesthesia, in which small electric currents are passed through the brain, intentionally triggered a brief seizure. ECT seems to cause changes in brain chemistry that can quickly reverse symptoms of certain mental illnesses.
Clinical Neurology
A branch of medicine involved in the treatment of nervous system disorders such as MS and paralysis
Psychiatry
A branch of medicine involved in treatment of disorders that affect the mind or psyche.
What is human behaviour a product of?
Product of brain activity
What is brain activity caused by?
- Product of genetics and environment
- Experience (trauma/disease)
- Genetic make-up and experience can interact, making a person more or less susceptible to future experience
- > Genetic mutation or under severe stress will detrimental effects to the brain.
What explains psychiatric disorders?
By the genetics and environment e.g. chronic stress from abusive relationship
Treatment of Mental Health Disorders
- Non-therapeutic e.g. cognitive behavioural
- Psychosocial support
- Pharmacotherapy
What type of disorder is depression?
Depression is characterised as an affective disorder
Affective disorder
A disorder of mood rather than thought/cognition.
What psychiatric disorder can cause premature death and disability?
Depression
Unipolar depression
- Mood swings in one direction
- Most common depressive illness
- 75% of cases reactive = induced by environmental factors
- 25% of cases endogenous = genetic
Bipolar depression
- Oscillation between depression and mania
- Less common
- Onset usually in adult life
- Strong hereditary tendancy
What is mania?
Excessive exhuberance, enthusiasm, self-confidence, impulsive actions, aggression, irritability, delusions of grandiose
How is depression diagnosed?
- Diagnosed through the DSM IV
- If 5 or more of the following symptoms have been presented during the same 2-weeks is diagnosed as depression:
- > Depressed mood nearly every day
- > Markedly diminished interest or pleasure in all or almost all, activities most of the day
- > weight loss
- > insomnia
- > retardation
- > fatigue or loss of energy
- > feelings of worthlessness of excessive or inappropriate guilt
- > diminised ability to think or concentrate, or indecivisness nearly every day
- > recurrent thoughts of death, recurrent suicidal ideation without a specific plan or a suicide attempt or a specific pain for committing suicide