Dental caries

Question 1

Gingivitis

Answer 1

Redness and swelling of the gingival tissues

Question 2

Periodontitis

Answer 2

Inflammation and either rapid(aggressive, generalized) or slower (chronic) destruction of the tissues supporting the tooth.

Question 3

Glucosyltranferase

Answer 3

Used by oral bacteria to colonize and adhere to structures. Mutations in enzyme prevents colonization of bacteria.

Question 4

Transferred from mother to infant

Answer 4

Gram-positive coccus

Question 5

Enamel smooth surface caries

Answer 5

S. mutans

Question 6

Enamel pits and fissures carires

Answer 6

S. mutans and lactobacilli

Question 7

Dentin caries

Answer 7

Lactobacilli

Question 8

Root caries

Answer 8

Various Actinomyces

Question 9

Sucrose metabolism from S. mutans

Answer 9

Creates long strand polymers (dextran) of sucrose molecules and allows bacteria to stick to gelatinous substrate.

Question 10

Surface protein antigens S. mutans

Answer 10

SA I/II, P1. Creates fuzzy coat and allows for adhesion.

Question 11

Polysaccharides-type specific antigens of S. mutans

Answer 11

Bind glucosyltransferase (GTF) to cell surface. GTF target for vaccine. Antibodies against prevent binding to GTF and prohibit caries formation

Question 12

Gingival Crevice

Answer 12

Contains lymphocytes, macrophages, PMN.

Question 13

Low titers of Parotide sIgA (PsIgA)

Answer 13

Low titers corresponds with increase dental caries. PsIgA recognizes all major serogroups of S. mutans. Blocks adhesion of S. mutans to provide caries resistance.