Dengue Flashcards
Etiologic agent of dengue
Dengue Virus
-members of the genus Flavivirus and family Flaviviridae
Four serotypes:
DENV-1
DENV-2
DENV-3
DENV-4
Vectors of dengue
Aedes aegypti
Aedes albopictus
Epidemiology of dengue
“Iceberg” or pyramid phenomenon - base of pyramid, most cases are symptomless followed by DF, DHF, DSS
Transmission of dengue
the female Ae. aegypti must bite an infected human during the viraemic phase of the illness that manifests two days before the onset of fever and lasts 4-5 days after onset of fever
Clinical course of dengue
Dengue case definition based on Severity
Dengue warning signs
Stepwise approach to
management of dengue
Clinical and laboratory criteria for patients who can be treated at home
Criteria for admission
Parameters and Frequency of Monitoring in Different Phases of Dengue Illness
Monitoring labs in different phases of dengue
Dengue with warning signs action plan
Dengue management in compensated shock
Dengue management in decompensated shock
Management of bleeding in dengue
Management of UGIB in dengue
Indications for ICU management in Dengue
- Recurrent or persistent shock
- Requirement for respiratory support (non-invasive and invasive ventilation)
- Significant bleeding
- Encephalopathy or encephalitis
Discharge criteria
- Afebrile for 48 hours.
- Improved general condition
- Improved appetite
- Stable hematocrit
- Rising platelet count
- No dyspnea or respiratory distress from pleural effusion or ascites
- Resolved bleeding episodes
- Resolution/recovery of organ dysfunction
