defence mechanisms and phagocytosis Flashcards

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1
Q

whats the function of an immune system?

A

a complex defence mechanism designed to protect from number of threats (pathogens, toxins, abnormal body cells, cells from other individuals - e.g. transplants)

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2
Q

what is a pathogen?

A

a microorganism or infectious agent that causes communicable disease

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3
Q

what is a cellular pathogen?

A

parasites (helmithes - tapeworm), protoza (plasmodia/ malaria), fungi (tinea - athletes foot), prokaryote (bacteria - leprosy)

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4
Q

what is a acellular pathogen (non-living) ?

A

virus ( e.g. HIV/ aids), prion (CJD)

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5
Q

what do membranes of all cells contain?

A

glycolipids and glycoproteins called antigens

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6
Q

what can antigens be identified by the immune system as?

A

either self or non-self

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7
Q

are antigens specific to each individual?

A

YES

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8
Q

what happens once the immune system has identified a non-self antigen?

A

it will innitiate an immune response

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9
Q

what happens once the immune system has identified a non-self antigen?

A

it will innitiate an immune response

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10
Q

what are the two immune responses and wgat do they do?

A

non-specific (innate) responses (they do barrier defences and phagocytosis), specific (adaptive) response (they do cell-mediated responses and humoral responses)

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11
Q

what are barrier defences for the body?

A

barrier defences are the first line of defence against a pathogen

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12
Q

what else do barrier defences do?

A

block a pathogen entry into the body or destroy and inactivate those that get in

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13
Q

what are the type of barrier defences?

A
  1. digestive enzyme
  2. skin
  3. lysosomes
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14
Q

what is the process of phagocytosis?

A

process carried by the white blood cell called a phagocyte

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15
Q

whats the first step of phagocytosis?

A

phagocytes engulf and digest foreign cells or particles

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16
Q

whats the second step of phagocytosis?

A

pathogen is engulfed and wrapped in a vesicle, forming a phagosome

17
Q

whats the third step of phagocytosis?

A

lysosomes within pagocyte fuse with the phagosome and Hydrolytic enzyme stored inside, break down the pathogen

18
Q

what happens in the fourth step of phagocytosis?

A

phagocyte then present the pathogens antigen on its plasma membrane, activates other immune cells.
it becomes an anitgen-presenting cell