Deck 6 Flashcards
Red flags for abdominal symptoms
Dysphagia, Tx resistant dyspepsia, Anorexia, unintentional weight loss (consider upper GI malignancy)
Anorexia, uninentional weight loss, haematemesis, altered bowel habit, iron deficiency, anaemia, unexplained rectal bleeding (consider lower GI malignancy).
Who might have pain free acute abdomen
Extremes of age, immunocompromised or last trimester of pregnancy
Acute abdomen epigastric, midgut and hindgut
Epigastric is oesophagus to D2
Midgut is D2 o transverse, rest is hindgut
Ischaemic bowel symptoms
Consider in patients with severe pain compared to signs (ischaemic until proven otherwise). Diffuse constant pain. Often unremarkable O/E. May have acidaemia and raised lactate. USe contrast CT to diagnose.
Pancreatitis
Look for 3xupper limit of amylase (lower can be perforation, ectopic or DKA). Check calcium and lipase
Appendicitis
Blockage of lumen (e.g. faecolith, lymph, tumour, parasites). Rebound tenderness over mcBurney’s point, Rovsigs sign, Psoas sign, obturator sign.
Imaging not essential for diagnosis, but USS/CT might be used.
Mana
Obturator sign
Pain on internal rotation of right hip (pelvic appendix)
Psoas sign
Pain on right hip extension - seen in retroperitoneal/retrocoecal appendix
Coeliac disease
T cell inflammation.
Gluten/prolamin stimulates abnormal mucosal response. Chronic inflammation and villous atrophy.
Coeliac disease histology
crypt hyperplasia, villous atrophy, lymphocytes in lamina propria
Coeliac disease clinical features and complications
mouth ulcer, diarrhoea, abdo pain, bloating, unexplained weight loss, malaise, weakness, steatorrhoea but 1/3 may be asymptomatic.
Skin manifestation is dermatitis herpetiformis (rare, but subepidermal skin blistering and itch)
Complications include malabsorption, anaemia, GI malignancy risk, T cell lymphoma risk, osteoporosis, hyposplenism
Coeliac disease RF
HLA DQ2, FHx, autoimmune (thyroid, T1DM)
Coeliac disease investigations
FBC, LFT, U&E, bone profile, Vitamin D, vitamin B12, haematinics, albumin, IgA tissue transglutimase (can do IgA endomysial antibody is only weakly positive).
Definitive by small bowel biopsy
IBS diagnosis
Consider if abdo pain/bloating/change in bowel habit for 6 months.
Diagnose if abdo pain either related to defecation and/or associated with altered stool frequency/appearance and 2 of:
- altered stool passage
- abdo bloating/distention/hardness
-symptoms aggrevated by eating
-passage of rectal mucus
In past 12 months with 12 weeks of symptoms
Additional symptoms may be lethargy, nausea, back ache and bladder symptoms
IBS
Functional disorder. Symptom based diagnosis.
Diet based Tx (avoid triggers, do more exercise) -loperamide for diarrhoea, antispasmodics for abdo cramps, peppermint oil/laxatives for constipation
Diverticulum definition
Outpouchings of bowel wall
Diverticulosis definition
Presence of diverticulum
Diverticulitis definition
Inflamed diverticulum
Diverticular disease RF
NSAIDs, FHx, smoking, obesity, male, Western diet, >50, meat eating, CT disease, PKD
Diverticular disease
Symptomatic diverticula
Colicky LLQ pain, relieved by defecation/flatus, made worse by eating. Get altered bowel habit, nausea, bloating and flatulence
Diverticulitis
left sided colic, constipation/overflow diarrhoea, symptoms mimic appendicitis but on left. Can get peritonitis symptoms if perforated- but steroids can mask presentation
Diverticular bleed
Erodes into vessel, causes large scale, painless bleed (typically dark red)
Ddx for diverticular disease
IBD, bowel cancer, ischaemic colitis, gynae causes, renal stones, IBS, coeliac disease
Admissions in diverticulitis
Uncontrolled pain, dehydration, significant comorbidities, immunocompromised, significant Pr bleed, 48h+ symptoms, peritonitic