Deck 12 Flashcards
Phimosis presentation and management
Can’t retract foreskin
May have weak stream, dribbling, haematuria, painful erections, recurrent UTIs
Management with hygiene, steroid cream, circumcision
Paraphimosis presentation and management
Swelling, painful erection, necrosis
Can use analgesia, compression, osmotic reduction (50% dextrose), puncture, cicumcision
Paraphimosis RF
Foreskin scaring, vigorous sexual activity, chronic valanitis, urinary catheterisation
Priapism
RF
Types
Erection >4h, despite ejaculation
Affects cavernosum
RF: sickle cell, sildenafil, antidepressants, cannibis, cocaine, leukaemia, pelvic tumour
Can be low flow or high flow
Low flow priapism
Blood doesn’t drain, intermittent but has risk of scarring if >4h. Can lead to impotence and fibrosis
High flow priopism
Rarer than low flow, less painful, often due to trauma/spinal cord injury
Tx may be cold pack and compression
Penis carcinoma
RF
Presentation
Mets
SCC of gland/prepuce
RF: phimosis, HPB 16 and 18,
Presents as burning itch, mass, ulceration
Can spread to liver/lung
Urethral stricture presentation
weak urinary stream, dyuria, incomplete voiding, may have retention
Urethral stricture causes and diagnosis
Narrowing. Can be injury, urethral instrumentation, infection, inflammatory conditions (e.g. lichen sclerosis)
Can be congenital or malignancy related
Diagnosed by cystoscopy
Painful testicular lumps
Generally strangulated inguinal hernias, testicular torsion or epididymo-orchitis
Painless scrotal lump
Often testicular tumour, haematocoele, epididymal cyst, varicocoele, hydrocoele
Varicocoele
Bag of worms, lump, dragging sensation, painless or dull ache
Disappears lying down, reappears on standing/valsalva
Needs investigating for malignancy obstructing left renal vein, so much do abdo exam
May have subfertility
Can manage with embolisation/ligation but ONLY if painful, infertility or occurance in children
Hydrocoele
Can be congenital, may be unilateral/bilateral
Peritoneal fluid collects between parietal and visceral tunica vaginalis (can be patent processus vaginalis (congenital or in raised intra abdo pressure such as fluid overload or dialysis) but can be imbalance of fluid secretion/reabsorption in older patients)
Can also occur in minor trauma, torsion or epididymitis
Aspiration possible but can reoccur inless roort cause resolves
Epididymal cyst/spermatocoele
Common, esp in middle age.
No increased malignancy risk.
Painless, smooth, well defined, fluctuant lumo, transilluminates. Separate to testes, chronic onset. Often superior and posterior
Epididymo-orchitis
Inflammation of epididimus/testicle, due to infection
In <35, often STI (Chlamydia/gonorrhoea), in >35 then more likely UTI (E/coli/pseudomonas)
Tender, oedema. Dysuria, fever, urethral discharge. Positive Phren sign (relief on testicular elevation)
Mumps can also cause orchitis so need to palpate parotid if fever prodrome
Bilateral mumps associated with infretility
If no STI/UTI symptoms then ? torsion instead
Orchitis causes
Can be extrapulmonary TB (also has thickened spermatic cord), or mumps (palpate parotid if fever prodrome)
Torsion of testicular appendage
Less painful than testicular torsion. Get small, blue nodule visible under the scrotum
No testicular elevation
Classically occurs at start of puberty
DDx for testicular torsion
Torsion of testicular appendage, epididymitis, indirect, inguinal strangulated hernia
RF for testicular cancer
RF: white, FHx testicular ca, undescended testes, infertility, infant hernia, klinefelters, hypospadia
Typical testicular cancer mets
Typically spread it to para-aortic lymph nodes, and to liver and lungs.
Semimona
50% of testicular cancer. From seminiferous tubules.
Peak age is 35
Malignant
Teratoma testicular cancer
Germ layer mix. Peak age 25
Can be embryonal, yolk sac(often benign but aggressive if malignant), choriocarcinoma (early lung mets, poor prognosis)
Non germ cell testicular cancers
Can be lymphoma, leydig tumour (respongs to LH, makes Testosterone or oestrogen), sertoli cells (can secrete oestrogen or teststerone)
Choriocarcinoma
Malignant trophoblast teratoma germ cell tumour. Poor prognosis. Early lung mets
Leydig tumour
Responds to LH, makes testosterone or oestrogen. Non germ cell
Sertoli cell tumour
Can secrete oestrogen or testosterone. Non germ cell tumour
Germ cell tumours
Seminomas or teratomas
Testicular cancer presentation
painless, fixed, film, irregular mass that does not transilluminate. May cause a secondary hydrocoele. May present with haematospermia. Can present with hormone secretion or mets (gynaecomastia, weight loss, back pain, dysponoea, SOB)
Investigation of testicular tumours
tumour markers (alpha fetoprotein in yolk sac tumour, b-hCG in teratomas and seminomas), USS, excision biopsy, staging (CT CAP). Royal marsden system for staging (1 is no mets, 2 is abdo node mets, 3 is supradiaphragmatic node mets and 4 is extra lymphatic mets)
Alpha fetoprotein for testicular cancer marker
Yolk sac teratoma (often benign but aggressive if malignant. Germ cell. Peak age is 25
b-hcG in testicular cancer
teratoma and seminoma investigation
milk production
15 lobules with milk glands empty into lactiferous duct
Breast lymph drainage
75% to ipsilateral axilla, 25% to internal mammary lymph gland (runs alongside internal mammary artery - crosses midline and allows spread)
benign breast lumps
tend to be smooth (examples are fibroadenoma, fibrocystic disease, breast cysts, breast abscesses, fat necrosis)
malignant breast lumps
Tend to be craggy, irregular, fixed
USS imaging in breast pathology
Generally under 35, if over this then mammorgram better.
USS used for lymph nodes.
Imaging in recurrent breast cancer
MRI
Imaging in lobular cancer
MRI
Core needle biopsy
USS or MRI guided.
Fibroadenoma
Most common benign. Stromal tissue. Common in young females
Painless, rubbery, firm, well demarcated. Highly mobile. No lymphadenopathy. Can be multiple, bilateral.
No treatment as 1/3 involute. if >4cm then patient may want removal