Day Two Flashcards
What are gluconate and triclosan used for?
Handwashing agents
What bacterium is considered the marker for intermediate sterilization?
M. tuberculosis
What medication is used to treat bacteremias caused by Pseudomonas?
Gentamicin
What two bacteria are found to play a role in ANUG?
Prevotella intermedia and Spirochetes
What two bacteria are associated with most generalized cases of perio?
Prevotella intermedia and Eikenella corrodens
What two bacteria are associated with most localized cases of perio?
AA and Capnocytophaga ochraceus
Describe Lacobacillus:
Regular, non-sporing, gram-positive bacteria
What bacteria is the main cause of smooth surface caries?
S. mutans
What bacteria is the main cause of root caries?
Acinomyces
What process describes change in the DNA of one bacterium by uptaking DNA that was from another, lysed bacterium?
Transformation
What process describes change in DNA from viruses in bacteria?
Transduction
What are the four stages of bacterial growth?
- Lag, 2. log, 3. Stationary and 4. Decline
What is another term that describes peptidoglycan?
Murein
What is the DNA region of prokaryotes called?
Nucleoid
Where are endotoxins located?
In the outer membrane of gram negative bacteria
What do Streptococcus, staphylococcus and Clostridium possess to spread throughout the body?
Hyaluronidase
What bacteria has coagulase and phospholipase to convert fibrinogen to fibrin and to lyse RBCs?
S. aureus
What bacteria has Lecithinase to destroy RBCs and other tissues?
C. perfringens
What do Clostridium, Bacteroides, AA and Bacillus possess?
Collagenase
What enzyme possessed by Strep and Staph enables the dissolving of blood clots?
Fibrinolysins
What type of streptococci produces a zone of incomplete, green hemolysis, complete hemolysis and incomplete hemolysis?
Alpha = incomplete, Beta = complete and Gamma = none
What protein seems to be connected to the virulence of a bacterial strain?
M protein
What superantigen is produced by Streptococcus pyogenes?
Pyrogenic exotoxin A
What bacteria causes strep throat, scarlet fever, erysipelas, impetigo, cellulitis, rheumatic fever, and acute poststreptococcal glomerulonephritis?
Streptococcus Pyogenes
What group of Strep is the leading cause of neonatal pneumonia, meningitis and sepsis?
Group B Strep
What morphology do bacteroides, fusobacterium and prevotella have?
Gram-negative anaerobic rods
What morphology do Pseudomonas, Bordetella, Neisseria, Brucella and Legionella have?
Gram-negative aerobic rods and cocci
What exotoxin rapidly destroys tissues?
Exotoxin B
What toxin causes the rash of scarlet fever?
Erythrogenic toxin
What disease is a neuromuscular disorder characterized by variable weakness of voluntary muscles, which often improves with rest and worsens with activity and is an abnormal immune response?
Myasthenia gravis
What disease is similar to Myasthenia gravis, but is caused by a inadequate release of ACh instead?
Eaton-Lambert Syndrome
What term describes toxic accumulation of unconjugated billirubin in the brain and spinal cord?
Kernicterus
What is used by the body to absorb vitamin B12?
Intrinsic Factor
What is caused by a lack of Vitamin B 12?
Pernicious anemia
What type of anemia is Pernicious anemia?
Megaloblastic
What disorder is caused by a inherited lack of production of one of the four chains of amino acids that make up hemoglobin?
Thalassemias
What disease is a result of inadequate destruction of red bone marrow?
Aplastic anemia
What disorder results from displaced hemopoietic tissues and is causes severe anemia with normal cytic and chormic erythrocytes?
Myelophthisic anemia
What anemia is associated with iron deficiency?
Microcytic anemia
What is the most common type of necrosis?
Coagulative necrosis
What type of injury is associated with mononuclear inflammatory cells (lymphocytes, plasma cells and macrophages) and the production of fibrous connective tissue?
Chronic Inflammation
What cells are involved in an acute inflammation response?
Basophils, mast cells and platelets
What is the scientific term for pus?
Exudate
What WBC predominates the cellular phase of an acute inflammation?
PMN
What cell marks the transition from acute to chronic inflammation?
Macrophages
What leukemia is the most common in children?
ALL
What leukemia is the most malignant?
AML
What leukemia is the least malignant?
CLL
What leukemia has two stages and is always fatal?
CML
What are large purpura spots called?
Ecchymoses
What disease is caused by a deficiency in platelets, leads to multiple bruises, petechiae, and hemorrhage into tissue?
Thrombocytopenic purpura (Werlhof’s disease)
What disease is a severe disease caused by a low platelet count due to thrombosis in terminal arterioles and capillaries of many organs?
Thrombotic Thrombocytopenic purpura
What is the most common cause of bleeding disorders?
Thrombocytopenia
What vitamin does Dicumarol interfere with?
Vitamin K
What does cirrhosis of the liver have to do with delayed blood clotting?
Patients with cirrhosis have less prothrobin in the blood and don’t have as good of clotting
What is Bernard-Soulier disease?
A hereditary platelet adhesion disorder
What leukemia is associated with Philadelphia chromosomes?
CML
What two types of leukemia are the most common in adults?
AML and CLL
What disease is characterized by mild to massive bleeding from an arterial vessel due to a tear in mucosa of the cardia or lower esophagus with vomiting or bright colored blood?
Mallory-Weiss syndrome
What disease is associated with difficulty swallowing both solids and liquids and is a nerve disorder that disrupts peristalsis?
Achalasia
What are Chvostek’s sign and Trousseau’s signs used to detect?
Tetany
What tetany-detecting sign is performed by tapping the facial nerve above the mandibular angle and testing the twitch of the upper lip?
Chvostek’s sign
What tetany-detecting sign is checked by applying a blood pressure cuff to the patient’s arm and checking for a spasm in the thumb?
Trousseau’s sign
What is trisomy 18 better known as?
Edward’s syndrome
What is trisomy 13 better known as?
Patau’s syndrome
What syndrome affects men and women equally and is a hereditary disease where many small lumps called juvenille polyps appear in the GI tract, has melanin pigmentation of the oral mucosa, and don’t have an increased risk of cancer from polyps?
Peutz-Jeghers syndrome
What syndrome is associated with polyps along with tumors of the CNS?
Turcots syndrome
What disease is associated with pigmentation, cirrhosis of the liver, degeneration of the basal ganglia, green pigment in the periphery of the cornea and problems metabolizing copper?
Wilson’s disease
What is the most severe immunodeficiency disease that causes a failure of stem cells to differentiate properly and results in the patient having neither B nor T lymphocytes?
Severe Combined Immunodeficiency Disease (SCID)
What disease is associated with immunodeficiency, eczema and only affects boys?
Wiskott-Aldrich syndrome
What disease is associated with a strange gait, visible dilation of blood vessels, and proneness to infections?
Ataxia-telangiectasia
What disease is an immunodeficiency where there is tons of IgE and repeated bacterial infections?
Hyperimmunoglobulin E syndrome (Job Syndrome)
What immunodeficiency is associated with no IgG and is sex linked?
X-linked agammaglobulinemia (Bruton’s agammaglobulinemia)
What causes Bruton’s agammaglobulinemia?
Mutation of B-cell protein tyrosine kinase
What does a lack of folic acid cause?
Anemia
What does a lack of Vitamin B1 cause?
Pins-and-needles sensation, especially in the feet
What does a lack of Vitamin B2 cause?
Sore tongue and cracks at the edge of mouth
What does a lack of Vitamin B12 cause?
Anemia, pins-and-needles sensation
What does a lack of Vitamin C cause?
Weakness, bleeding gums
What does a lack of Vitamin D cause?
Bone thinning
What does a lack of Protein cause?
Tissue swelling
What is the name of the rare condition where infection of the intestine causes malabsorption, causes skin darkening, inflamed and painful joints and diarrhea?
Whipple’s disease
What test is used to detect E. Coli, Vibrio Cholerae, and Staph. aureus?
ELISA
What defines an endemic?
Infection constantly present at low levels in a specific population
What is the most common cause of encephalitis?
Viral infection
What disease is a overwhelming, rapidly-progressing infection caused by Neisseria meningitidis?
Waterhous-Friderichsen syndrome
What happens in the first stage of Syphilis?
Non-painful chancre emerges
What happens in the second stage of Syphilis?
Maculopapular rash and condyloma lata
What happens in the third stage of Syphilis?
Gumma appears and neurologic symptoms are evident
What is the best treatment for Syphilis?
Parenteral Penicillin G
What is the name of the warty soft tissue enlargement caused by HPV?
Condyloma acuminatum
Salpingitis is associated with infection from which type of bacteria?
Chlamydia
What medication interferes with Influenza A’s ability to attach and uncoat?
Amantadine
What typically results from a bacterial infection (WBC-wise)?
Leukocytosis
What typically results from a viral infection (WBC-wise)?
Leukopenia
Describe rubella:
A member of togavirus that is enveloped with an icosahedral nucleocapsid and negative-stranded, double stranded RNA genome
What are the consequences of a congenital rubella syndrome for the baby?
Malformation of the heart, eyes and brain
What term describes condensation of cell nucleus with chromatin clumping?
Pyknosis
What term describes shrinkage of cell nuclei and condensation of the chromatin?
Karyopyknosis
What term describes the fragmentation of the cell nucleus and chromatin?
Karyorrhexis
What disease causes the kidney to fail to develop and creates cysts deep within the kidney?
Medullary cystic disease
What disease causes the kidneys to appear spongy and dilates the urine-containing tubules of the kidneys?
Medullary sponge kidney
What syndrome has symptoms of proteinuria, hypoalbuminemia, hyperlipidemia and edema?
Nephrotic Syndrome
What sign would suggest pyelonephritis?
WBCs in urine
What sign would suggest nephritic syndrome?
RBCs in urine
What symptom would accompany infarction of the kidney?
Few RBCs in urine
Glomerulonephritis often follows an infection by which type of bacteria?
Streptococcus
What term describes a malignant neoplasm’s growth in which there is no differentiation to suggest a particular cell type?
Anaplasia
What neoplasm exhibits prickle cells and keratin pearls?
Squamous Cell Carcinoma
What is the key difference in histology between malignant lymphomas and Hodgkin’s disease?
Reed-sternberg cells are present in Hodgkin’s disease
Where is the most likely place to develop malignant neoplasms in the GI tract?
Colon/rectum
What are the most common pelvic tumors?
Uterine fibroids