Day 9 Review - GU1, GU2, GU3

Question 1

HSP p/w

Answer 1

(1) Palpable purpura LE (not due to thrombocytopenia), (2) GI (ab pain, vomiting, guaic positive stool, intussusception), (3) Renal disease (hematuria, proteinuria, etc.), (4) Arthritis (transient, multiple joints, LE like purpura)

Question 2

Ranson’s criteria components (not values)

Answer 2

On Admission: GA LAW - (1) Glucose (2) AST (3) LDH (4) Age (5) WBC; Initial 48 hrs after admission: C-HOBBS (1) Ca (2) Hct (3) O2 (4) BUN (5) Base Deficit (6) Sequestration of fluid

Question 3

Tx for diarrheal illnesses: Entamoeba histolytica

Answer 3

Metronidazole

Question 4

Tx for diarrheal illnesses: Giardia

Answer 4

Metronidazole

Question 5

Tx for diarrheal illnesses: Salmonella

Answer 5

Quiniolone or TMP/SMX (Bactrim); Only in high risk or severe illness

Question 6

Tx for diarrheal illnesses: Shigella

Answer 6

Like Salmonella, Quiniolone or TMP/SMX (Bactrim)

Question 7

Tx for diarrheal illnesses: Campylobacter

Answer 7

Erythromycin

Question 8

Lung CA: elevated ACTH causing glucocorticoid excess in Cushing syndrome

Answer 8

Small cell lung cancer

Question 9

Lung CA: elevated PTHrP causing hypercalcemia

Answer 9

Squamous cell lung CA

Question 10

Lung CA: elevated ADH, resulting in SIADH causing hyponatremia

Answer 10

Small cell lung Ca

Question 11

Lung CA: Antibodies to presynaptic calcium channel receptors causing Lambert-Eaton syndrome

Answer 11

Small cell lung cancer

Question 12

Vasculitis: weak pulses in upper extremities

Answer 12

Takyasu’s arteritis

Question 13

Vasculitis: necrotizing granulomas of lung & necrotizing glomerulonephritis

Answer 13

Wegener’s granulomatos

Question 14

Vasculitis: Necrotizing immune complex inflammation of visceral and renal vessels

Answer 14

Polyarteritis nodosa

Question 15

Vasculitis: Young male smokers

Answer 15

Berger’s disease

Question 16

Vasculitis: Young Asian women

Answer 16

Takaysu’s

Question 17

Vasculitis: Young asthmatics

Answer 17

Churg-Strauss (eosinophilia, asthma)

Question 18

Vasculitis: infants, young children involving coronary

Answer 18

Kawasaki

Question 19

Vasculitis: most common

Answer 19

Temporal aka Giant Cell arteritis

Question 20

Vasculitis: assoc. w/ Hep B infx

Answer 20

Polyarteritis nodosa

Question 21

Vasculitis: Occlusion of ophthalmic artery can lead to blindness

Answer 21

Temporal aka Giant Cell arteritis

Question 22

Vasculitis: perforation of nasal septum

Answer 22

Wegener’s granulomatosis

Question 23

Vasculitis: unilateral HA & jaw claudication

Answer 23

Temporal aka Giant Cell arteritis

Question 24

Lipid lowering agent: s/e of facial flushing

Answer 24

Niacin

Question 25

Lipid lowering agent: s/e of elevated LFTs & myositis

Answer 25

Fibrates & Statins (not mix them together in regimen)

Question 26

Lipid lowering agent: s/e of GI discomfort and bad taste

Answer 26

Bile acid resins (e.g., cholestyramine)

Question 27

Lipid lowering agent: best effect on HDL

Answer 27

Niacin

Question 28

Lipid lowering agent: best effect of TGs/VLDL

Answer 28

Fibrates

Question 29

Lipid lowering agent: best effect on LDL

Answer 29

Statins

Question 30

Lipid lowering agent: binds C. diff toxin

Answer 30

Cholestyramine (which is a bile acid resin)

Question 31

Drugs known for causing elevated prolactin levels

Answer 31

Psychiatric drugs (e.g., phenathiazines, risperidone, haloperidol), Methyldopa, Verapamil