Day 13 Review - Gyn1, Gyn2, Gyn3 Flashcards
Blood cell pathology: Assoc w/ EBV, especially in Africa
Burkitt’s Lyphoma
Blood cell pathology: Reed Sternberg cells
Hodgkin Disease
Blood cell pathology: Bence Jones proteins, osteolytic lesions, High calcium
Multiple Myeloma; Npte: Hypercalcemia due to local osteolytic factors
Blood cell pathology: t(14;18)
Follicular lymphoma
Blood cell pathology: Most common lymphoma in US
Diffuse large B cell lymphoma
Blood cell pathology: t(8;14)
Burkitt’s lymphoma
Blood cell pathology: t(9;22)
CML (Philadelphia chromosome - 15% adult ALL’s also have this)
Blood cell pathology: Most common form of Hodgkin lymphoma
Nodular sclerosis
Blood cell pathology: Starry sky pattern due to phagocytosis of apoptotic tumor cells
Burkitt’s lymphoma
Blood cell pathology: High H & H, pruritus (especially after hot bath/shower), burning pain in hands/feet
Polycythemia vera
Blood cell pathology: Blood smear showing hair-like projections, Splenomegaly
Hairy B cell leukemia
Distinguish orbital cellulitis v. periorbital cellulitis
ORBITAL: pain w/ eye movement, proptosis, ophthalmoplegia, double/decreased vision ; PERIORBITAL:
Bupropion contraindications
Lowers seizure threshold; Contraindications: Eating disorders, seizure disorder, withdrawing from alcohol or benzos, & MAOis in last 2 wks
Tx Serotonin syndrome
Stop serotingergic agent; Supportive (decrease muscle tone, may need sedation - benzos/intubation/paralysis); NOT use Dantrolene (reserved for neuroleptic malignant syndrome)
BPPV dx & tx
Classic H & P: vertigious worse w/ rollover in bed, laydown, or raise head up; Dx w/ Dix-Hallpike maneuver; Tx - Maneuvers (e.g., Epley)
Tx acute angle closure glaucoma
Different drugs may be used; Acetazolamide, Mannitol, Beta blockers, Alpha adrengergics, Prostaglandins, Cholinergic agonists (e.g., Pilocarpine)
Antidotes: Organophosphate (anticholinesterase) toxicity
Atropine + Pralidoxime (reverse blockade of acetylcholinesterase)
Antidotes: Mercury
Dimercaprol, also succimer
Antidotes: Carbon monoxide
100% hyperbaric oxygen
Antidotes: Heparin
Protamine sulfate
Antidotes: Isoniazid
B6 (pyridoxine)
Heart murmur: Diastolic murmur heard best LL sternum, increases with inspiration
Tricuspid stenosis
Heart murmur: Late diastolic murmur w/ opening snap, no change with inspiration
Mitral stenosis
Heart murmur: Systolic murmur heard best in 2nd R interspace
Aortic stenosis
Heart murmur: Systolic heard best in 2nd L interspace
Pulmonic stenosis
Heart murmur: Late systolic murmur heard best at apex
Mitral prolapse
Heart murmur: Diastolic murmur with widened pulse pressure
Aortic regurgitation
Heart murmur: Holosytolic murmur louder with inspiration, best heard in LL sternum
Tricuspid regurgitation
Heart murmur: Holosytolic murmur, heard at apex, radiates to axilla
Mitral regurgitation